SCHEMBL3347866

SCHEMBL3347866

C[Si](C)(C)O[Si](C)(c1ccccc1)c1ccccc1.c1ccc([Si](O[Si](c2ccccc2)(c2ccccc2)c2ccccc2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.34
ESR2 Q92731 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL810787 0.91 ESR1 (0.39) ESR1ESR2
SCHEMBL9577405 0.89 ESR1 (0.38) ESR1ESR2
SCHEMBL2048191 0.86 ESR1 (0.39) ESR1ESR2
SCHEMBL433139 0.81 ESR1 (0.42) ESR1ESR2
SCHEMBL335769 0.81 TSHR (0.35) ESR1ESR2
SCHEMBL27101096 0.80 ESR1 (0.35) ESR1ESR2
SCHEMBL5552262 0.80 ESR1 (0.35) ESR1ESR2
SCHEMBL30003124 0.78 ESR1 (0.34) ESR1ESR2
SCHEMBL31510043 0.78 ESR1 (0.34) ESR1ESR2
SCHEMBL94183 0.78 ESR1 (0.34) ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2186832-B1 Process for the preparation of an unsupported, solid metallocene catalyst system and its use in polymerization of olefins BOREALIS AG (AT) 2012-09-12 EP disclosed
EP-2186832-A1 Process for the preparation of an unsupported, solid metallocene catalyst system and its use in polymerization of olefins Borealis AG (AT) 2010-05-19 EP disclosed
WO-2010052239-A1 PROCESS FOR THE PREPARATION OF AN UNSUPPORTED, SOLID METALLOCENE CATALYST SYSTEM AND ITS USE IN POLYMERIZATION OF OLEFINS BOREALIS AG (AT) 2010-05-14 WO disclosed