⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12079446 | 0.65 | — | — | |
| SCHEMBL8105800 | 0.61 | — | — | |
| SCHEMBL334873 | 0.61 | — | — | |
| SCHEMBL12094183 | 0.60 | DYRK1A (0.39) | — | |
| SCHEMBL3302453 | 0.60 | PIK3CG (0.42) | — | |
| SCHEMBL297724 | 0.57 | — | — | |
| SCHEMBL2262306 | 0.56 | — | — | |
| SCHEMBL23913613 | 0.56 | DYRK1A (0.33) | — | |
| SCHEMBL17927920 | 0.56 | DYRK1A (0.33) | — | |
| SCHEMBL2008710 | 0.53 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 124 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024035950-A1 | INHIBITORS OF KIF18A AND USES THEREOF | ACCENT THERAPEUTICS, INC. (US) | 2024-02-15 | — | — | WO | claimed |
| US-11632957-B2 | Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto | CORTEVA AGRISCIENCE LLC (US) | 2023-04-25 | — | — | US | claimed |
| US-20200196607-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2020-06-25 | — | — | US | claimed |
| EP-3578543-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | Dow AgroSciences LLC (US) | 2019-12-11 | — | — | EP | claimed |
| EP-3283459-B1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2019-05-22 | — | — | EP | claimed |
| US-9781935-B2 | Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto | DOW AGROSCIENCES LLC (US) | 2017-10-10 | — | — | US | claimed |
| EP-2681214-B1 | BRIDGED PIPERIDINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2017-03-22 | — | — | EP | claimed |
| US-20160304522-A1 | Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto | DOW AGROSCIENCES LLC (US) | 2016-10-20 | — | — | US | claimed |
| US-8703763-B2 | Bridged piperidine derivatives | HOFFMANN-LA ROCHE INC. (US) | 2014-04-22 | — | — | US | claimed |
| EP-2681214-A1 | BRIDGED PIPERIDINE DERIVATIVES | F.HOFFMANN-LA ROCHE AG (CH) | 2014-01-08 | — | — | EP | claimed |
| WO-2012116965-A1 | BRIDGED PIPERIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-09-07 | — | — | WO | claimed |
| US-20120225884-A1 | BRIDGED PIPERIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-09-06 | — | — | US | claimed |
| EP-0888297-B1 | N-ARYLSULFILIMINE COMPOUNDS AND THEIR USE AS CATALYSTS IN THE PREPARATION OF N-ARYLARYLSULFONAMIDE COMPOUNDS | DOW AGROSCIENCES LLC (US) | 2000-08-30 | — | — | EP | claimed |
| US-5973148-A | N-arylsulfilimine compounds and their use as catalysts in the preparation of N-arylarylsulfonamide compounds | DOW AGROSCIENCES LLC (US) | 1999-10-26 | — | — | US | claimed |
| WO-2024035950-A1 | INHIBITORS OF KIF18A AND USES THEREOF | ACCENT THERAPEUTICS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |
| US-20230180761-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | CORTEVA AGRISCIENCE LLC (US) | 2023-06-15 | — | — | US | disclosed |
| US-11632957-B2 | Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto | CORTEVA AGRISCIENCE LLC (US) | 2023-04-25 | — | — | US | disclosed |
| US-5488109-A | 5-alkoxy[1,2,4]triazolo[1,5-c]pyrimidine-2(3H)--thione compounds and their use in the preparation of and 2-chlorosulfonyl-5-alkoxy[1,2,4]triazolo[1,5-c]-pyrimidine compounds | DOWELANCO (US) | 1996-01-30 | — | — | US | disclosed |
| EP-0678092-A1 | 5-ALKOXY 1,2,4]TRIAZOLO 1,5-C]PYRIMIDINE-2(3H)-THIONE COMPOUNDS AND THEIR USE IN THE PREPARATION OF 2,2'-DITHIOBIS(5-ALKOXY 1,2,4]TRIAZOLO 1,5-C]-PYRIMIDINE) AND 2-CHLOROSULFONYL-5-ALKOXY 1,2,4]TRIAZOLO 1,5-C]PYRIMIDINE COMPOUNDS | DOWELANCO (US) | 1995-10-25 | — | — | EP | disclosed |
| WO-1995012596-A1 | 5-ALKOXY[1,2,4]TRIAZOLO[1,5-C]PYRIMIDINE-2(3H)-THIONE COMPOUNDS AND THEIR USE IN THE PREPARATION OF 2,2'-DITHIOBIS(5-ALKOXY[1,2,4]TRIAZOLO[1,5-C]-PYRIMIDINE) AND 2-CHLOROSULFONYL-5-ALKOXY[1,2,4]TRIAZOLO[1,5-C]PYRIMIDINE COMPOUNDS | DOWELANCO (US) | 1995-05-11 | — | — | WO | disclosed |