Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12890924 | 0.83 | — | — | |
| SCHEMBL4188929 | 0.83 | — | — | |
| SCHEMBL12890928 | 0.83 | — | — | |
| Ammonia Solution, Strong SCHEMBL9446685 | 0.81 | MEN1 (0.41) | TSHRMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL23200430 | 0.80 | TSHR (0.40) | TSHRMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL16774771 | 0.78 | — | — | |
| SCHEMBL18465494 | 0.77 | ALDH1A1 (0.39) | TSHRALDH1A1LMNATDP1 | |
| SCHEMBL356446 | 0.77 | ALDH1A1 (0.39) | TSHRALDH1A1LMNATDP1 | |
| SCHEMBL11210595 | 0.77 | — | — | |
| SCHEMBL31693092 | 0.77 | ALDH1A1 (0.39) | TSHRALDH1A1LMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010041194-A1 | TRICYCLIC OXAZOLIDINONE ANTIBIOTIC COMPOUNDS | ACTELION PHARMACEUTICALS LTD (CH) | 2010-04-15 | — | — | WO | disclosed |
| WO-2010042391-A2 | HIV INTEGRASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2010-04-15 | — | — | WO | disclosed |