SCHEMBL3348812

SCHEMBL3348812

CCc1cnc(N2CCC(Oc3ccc(CCNc4ccc(S(C)(=O)=O)nc4C)cc3)CC2)nc1

nearest known ligand 0.48

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 19/20 0.48
ACACB O00763 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3346737 0.92 GPR119 (0.49) GPR119
SCHEMBL3344880 0.85 GPR119 (0.50) GPR119
SCHEMBL3346772 0.84 GPR119 (0.47) GPR119ACACB
SCHEMBL3348808 0.84 ACACB (0.47) GPR119ACACB
SCHEMBL3346467 0.84 GPR119 (0.46) GPR119
SCHEMBL3347542 0.83 GPR119 (0.52) GPR119
SCHEMBL3341603 0.82 GPR119 (0.47) GPR119
SCHEMBL3344970 0.82 GPR119 (0.45) GPR119
SCHEMBL3342729 0.81 GPR119 (0.45) GPR119
SCHEMBL3342662 0.81 GPR119 (0.53) GPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010048149-A2 HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE KALYPSYS, INC. (US) 2010-04-29 WO disclosed