Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 8/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5931431 | 0.87 | EPHX2 (0.62) | EPHX2KMT2ASRD5A1SRD5A2LMNA | |
| SCHEMBL3341482 | 0.87 | EPHX2 (0.47) | EPHX2KMT2ASRD5A1SRD5A2LMNA | |
| SCHEMBL5931838 | 0.84 | EPHX2 (0.65) | EPHX2LMNAFFAR4 | |
| SCHEMBL19610147 | 0.84 | EPHX2 (0.50) | EPHX2KMT2ASRD5A1SRD5A2LMNA | |
| SCHEMBL19023393 | 0.83 | OPRK1 (0.52) | EPHX2KMT2AMEN1 | |
| SCHEMBL5243542 | 0.83 | SRD5A1 (0.50) | EPHX2KMT2ASRD5A1SRD5A2 | |
| SCHEMBL213590 | 0.83 | SRD5A1 (0.50) | EPHX2KMT2ASRD5A1SRD5A2LMNA | |
| SCHEMBL5271411 | 0.82 | EPHX2 (0.59) | EPHX2SRD5A1 | |
| SCHEMBL19610267 | 0.82 | FFAR4 (0.51) | EPHX2SRD5A1SRD5A2LMNAFFAR4 | |
| SCHEMBL1648387 | 0.82 | SMN1; SMN2 (0.61) | EPHX2KMT2ALMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010048149-A2 | HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2010-04-29 | — | — | WO | disclosed |