Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 20/20 | 0.78 |
| ▸ | PPARG | P37231 | 14/20 | 0.78 |
| ▸ | PPARA | Q07869 | 7/20 | 0.78 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.75 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10271422 | 0.90 | PPARD (0.81) | PPARDPPARGPPARACYP2C9 | |
| SCHEMBL10221075 | 0.88 | PPARD (1.00) | PPARDPPARGPPARACYP2C9CYP3A4 | |
| SCHEMBL4729062 | 0.87 | PPARD (0.60) | PPARDPPARGPPARACYP2C9CYP3A4 | |
| SCHEMBL10221097 | 0.87 | PPARD (0.99) | PPARDPPARGPPARACYP2C9CYP3A4 | |
| SCHEMBL10221459 | 0.87 | PPARD (0.65) | PPARDPPARGPPARACYP2C9CYP3A4 | |
| SCHEMBL10221152 | 0.86 | PPARD (0.74) | PPARDPPARGPPARACYP2C9 | |
| SCHEMBL10221121 | 0.86 | PPARD (1.00) | PPARDPPARGPPARACYP2C9CYP3A4 | |
| SCHEMBL334583 | 0.85 | PPARD (0.71) | PPARDPPARGPPARACYP2C9 | |
| SCHEMBL10221467 | 0.85 | PPARD (1.00) | PPARDPPARGPPARACYP2C9CYP3A4 | |
| SCHEMBL10221463 | 0.84 | PPARD (0.71) | PPARDPPARGPPARACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8097610-B2 | Derivative having PPAR agonistic activity | SHIONOGI & CO., LTD. (JP) | 2012-01-17 | — | — | US | disclosed |
| US-8097610-B2 | Derivative having PPAR agonistic activity | SHIONOGI & CO., LTD. (JP) | 2012-01-17 | — | — | US | disclosed |
| US-20090286974-A1 | Derivative having ppar agonistic activity | SHIONOGI & CO., LTD. (JP) | 2009-11-19 | — | — | US | disclosed |
| US-20090286974-A1 | Derivative having ppar agonistic activity | SHIONOGI & CO., LTD. (JP) | 2009-11-19 | — | — | US | disclosed |
| EP-1939189-A1 | DERIVATIVE HAVING PPAR AGONISTIC ACTIVITY | SHIONOGI & CO., LTD. (JP) | 2008-07-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286974-A1 | Derivative having ppar agonistic activity | PPARD, PPARA, PPARG | PPARD 1/4885PPARG 3/4885PPARA 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.