Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 20/20 | 0.60 |
| ▸ | PPARG | P37231 | 14/20 | 0.60 |
| ▸ | PPARA | Q07869 | 6/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL334892 | 0.87 | PPARD (0.78) | PPARDPPARGPPARACYP2C9CYP3A4 | |
| SCHEMBL334111 | 0.79 | PPARD (0.47) | PPARDPPARGPPARACYP2C9 | |
| SCHEMBL10221459 | 0.79 | PPARD (0.65) | PPARDPPARGPPARACYP2C9CYP3A4 | |
| SCHEMBL10271422 | 0.77 | PPARD (0.81) | PPARDPPARGPPARACYP2C9 | |
| SCHEMBL334494 | 0.77 | PPARD (0.44) | PPARDPPARGPPARACYP2C9CYP3A4 | |
| SCHEMBL10221075 | 0.75 | PPARD (1.00) | PPARDPPARGPPARACYP2C9CYP3A4 | |
| SCHEMBL10221152 | 0.75 | PPARD (0.74) | PPARDPPARGPPARACYP2C9 | |
| SCHEMBL334583 | 0.75 | PPARD (0.71) | PPARDPPARGPPARACYP2C9 | |
| SCHEMBL10221097 | 0.74 | PPARD (0.99) | PPARDPPARGPPARACYP2C9CYP3A4 | |
| SCHEMBL334495 | 0.73 | PPARD (0.41) | PPARDPPARGPPARACYP2C9CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1939189-A1 | DERIVATIVE HAVING PPAR AGONISTIC ACTIVITY | SHIONOGI & CO., LTD. (JP) | 2008-07-02 | — | — | EP | disclosed |