SCHEMBL33494

SCHEMBL33494

COC(=O)c1ccc(CBr)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LOXL2 Q9Y4K0 1/20 0.66
CYP4A11 Q02928 2/20 0.59
CYP4F2 P78329 1/20 0.58
CA1 P00915 3/20 0.57
CA2 P00918 3/20 0.57
TDP1 Q9NUW8 1/20 0.57
CA12 O43570 1/20 0.57
CA7 P43166 1/20 0.57
CA9 Q16790 1/20 0.57
CA14 Q9ULX7 1/20 0.57
MAPT P10636 2/20 0.57
TSHR P16473 2/20 0.54
MEN1 O00255 1/20 0.53
KMT2A Q03164 1/20 0.53
ALDH1A1 P00352 2/20 0.52
CES2 O00748 1/20 0.52
CES1 P23141 1/20 0.52
HPGD P15428 2/20 0.51
KDM4E B2RXH2 1/20 0.51
NPC1 O15118 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4050879 0.98 LOXL2 (0.63) LOXL2CYP4A11CYP4F2CA1CA2
Bromide SCHEMBL4809006 0.98 LOXL2 (0.63) LOXL2CYP4A11CYP4F2CA1CA2
SCHEMBL1774489 0.94 LOXL2 (0.59) LOXL2CYP4A11CYP4F2CA1CA2
SCHEMBL7021444 0.94 LOXL2 (0.59) LOXL2CYP4A11CYP4F2CA1CA2
Acetonitrile SCHEMBL23628987 0.91 LOXL2 (0.56) LOXL2CYP4A11CYP4F2CA1CA2
SCHEMBL2839451 0.91 CA1 (0.56) LOXL2CYP4A11CYP4F2CA1CA2
4-Methylbenzoic Acid Methyl Ester SCHEMBL7376893 0.89 TDP1 (0.67) LOXL2CYP4A11CYP4F2CA1CA2
SCHEMBL7376896 0.88 LOXL2 (0.53) LOXL2CYP4A11CYP4F2CA1CA2
Toluene SCHEMBL27262094 0.88 TDP1 (0.59) LOXL2CYP4A11CA1CA2TDP1
SCHEMBL28652088 0.87 NPC1 (0.65) MAPTTSHRMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5294 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117285484-B Benzothiadiazine 1, 1-dioxide compounds inhibiting HDAC6 enzyme, preparation method and application thereof Shanghai Pharmaceutical Industry Research Institute Co.,Ltd. (CN) 2026-05-26 CN claimed
EP-4722203-A1 3,4-DIHYDROPHTHALAZIN-1(2H)-ONE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF Academy of Military Medical Sciences (CN) 2026-04-08 EP claimed
CN-115616056-B Photoelectrochemical aptamer sensor and preparation method and application thereof 温州医科大学 2025-04-25 CN claimed
WO-2024251080-A1 3,4-DIHYDROPHTHALAZIN-1(2H)-ONE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF 中国人民解放军军事科学院军事医学研究院 2024-12-12 WO claimed
EP-4452952-A1 A PREPARATION OF QUINAZOLINEDIONES AND USE THEREOF Council of Scientific and Industrial Research, an Indian Registered Body Incorporated under Regn. of Soc. Act (Act XXI of 1860) (IN) 2024-10-30 EP claimed
CN-116003404-B Risperidone artificial hapten and artificial antigen as well as preparation methods and application thereof 杭州同舟生物技术有限公司 2024-10-01 CN claimed
CN-115611823-B 1,2, 4-Triazole-phenyl hydroxamic acid compound, preparation method and application 新天地医药技术研究院(郑州)有限公司 2024-09-27 CN claimed
US-12065411-B1 Methyl 4-((5-(3-fluorophenyl)-4-phenyl-4H-1,2,4-triazol-3-ylthio)methyl)benzoate as an antimicrobial compound King Faisal University (SA) 2024-08-20 US claimed
CN-118359611-A Imidazo [1,2-a ] pyridine derivative and preparation method and application thereof 郑州大学 2024-07-19 CN claimed
CN-113980117-B Fenpyroximate antigen and preparation method and application thereof 西南大学 2024-07-12 CN claimed
CN-107141286-A The synthetic method of 3 aryl substituted indole piperazines 南京理工大学 2017-09-08 CN claimed
CN-106928079-A Trefanocide haptens and its preparation method and application 广东第二师范学院 2017-07-07 CN claimed
CN-104610166-B Pyrimidine benzyl hydroxamic acid histone deacetylases inhibitor and preparation method and application 山东大学 2017-06-13 CN claimed
CN-106318380-A Tetraphenyl ethylene derivative ion complex and preparation method thereof 天津大学 2017-01-11 CN claimed
CN-103923015-A Two selective ionic liquids and synthesis method thereof UNIV BEIJING TECHNOLOGY 2014-07-16 CN claimed
CN-103819390-A Synthesis method of RAFT chain transfer agent containing terminal hydroxyl NANJING UNIVERSITY OF TECHNOLOGY 2014-05-28 CN claimed
WO-2011004384-A2 PROCESS FOR THE PREPARATION OF EPROSARTAN GLOCHEM INDUSTRIES LIMITED (IN) 2011-01-13 WO claimed
WO-2009084028-A2 IMPROVED PROCESS FOR MANUFACTURING ANHYDROUS (E)-3-[2-BUTYL-1- {(4-CARBOXYPHENYL) METHYL}-1H-IMIDAZOLE-5-YL]-(THIOPHEN-2- YLMETHYL)PROP-2-ENOIC ACID METHANE SULFONATE NEULAND LABORATORIES LTD (IN) 2009-07-09 WO claimed
WO-2007117482-A2 RENIN INHIBITORS VITAE PHARMACEUTICALS, INC. (US) 2007-10-18 WO claimed
US-7001973-B2 Catalyst and process for preparing low-viscosity and color-reduced polyisocyanates containing isocyanurate groups DEGUSSA AG (DE) 2006-02-21 US claimed