Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7370494 | 0.83 | ALDH1A1 (0.54) | ALDH1A1CYP2A6KDM4ECYP3A4LMNA | |
| SCHEMBL1004990 | 0.81 | ALDH1A1 (0.62) | ALDH1A1CYP2A6KDM4ECYP3A4LMNA | |
| SCHEMBL12785240 | 0.78 | KDM4E (0.57) | ALDH1A1KDM4ECYP3A4LMNATP53 | |
| SCHEMBL2771378 | 0.78 | KDM4E (0.57) | ALDH1A1KDM4ECYP3A4LMNATP53 | |
| SCHEMBL2771380 | 0.78 | KDM4E (0.57) | ALDH1A1KDM4ECYP3A4LMNATP53 | |
| SCHEMBL3184498 | 0.77 | ALDH1A1 (0.58) | ALDH1A1CYP2A6KDM4ECYP3A4LMNA | |
| SCHEMBL1253022 | 0.77 | ALDH1A1 (0.58) | ALDH1A1CYP2A6KDM4ECYP3A4LMNA | |
| Hydrochloric Acid SCHEMBL11482677 | 0.77 | KDM4E (0.55) | ALDH1A1KDM4ECYP3A4LMNATP53 | |
| Hydrochloric Acid SCHEMBL11482674 | 0.77 | KDM4E (0.55) | ALDH1A1KDM4ECYP3A4LMNATP53 | |
| SCHEMBL293710 | 0.76 | ALDH1A1 (0.56) | ALDH1A1CYP2A6KDM4ECYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109665966-A | A kind of preparation method of succinic acid desmethylvenlafaxine compound | 山东蒲济医药科技有限公司 | 2019-04-23 | — | — | CN | claimed |
| CN-102093233-A | Method for preparing 1-[2-amino-1-(p-methoxy phenyl) ethyl] cyclohexanol hydrochloride | SHANGHAI ECUST BIOMEDICINE CO LTD | 2011-06-15 | — | — | CN | claimed |
| CN-100364966-C | Process of synthesizing 1-[2-amino-1-(p-methoxylphenyl)-ethyl] cyclohexanol formate | SHANGHAI YABEN CHEMISTRY CO LT (CN) | 2008-01-30 | — | — | CN | claimed |
| CN-1847219-A | Process of synthesizing 1-[2-amino-1-(p-methoxylphenyl)-ethyl] cyclohexanol formate | SHANGHAI YABEN CHEMISTRY CO LT (CN) | 2006-10-18 | — | — | CN | claimed |
| CN-1225356-A | Synthetic method of 1-[2-amino-1-(P-methoxybenzyl) ethyl] cyclohexanol | UNIV EAST CHINA SCIENCE & ENG (CN) | 1999-08-11 | — | — | CN | claimed |
| CN-104382924-B | N6 substituted adenosines derivative and N6 substituted adenines derivatives and application thereof | 中国医学科学院药物研究所 | 2017-12-22 | — | — | CN | disclosed |
| CN-104326927-B | A kind of preparation method of 1-[2-amino-1-(4-methoxyphenyl) ethyl] Hexalin sulfate | 齐鲁天和惠世制药有限公司 | 2016-06-15 | — | — | CN | disclosed |
| CN-104382924-A | N6-substituted adenosine derivative and N6-substituted adenine derivative and application thereof | INST MATERIA MEDICA CAMS | 2015-03-04 | — | — | CN | disclosed |
| CN-102093233-A | Method for preparing 1-[2-amino-1-(p-methoxy phenyl) ethyl] cyclohexanol hydrochloride | SHANGHAI ECUST BIOMEDICINE CO LTD | 2011-06-15 | — | — | CN | disclosed |
| WO-2010046808-A2 | A PROCESS FOR THE PREPARATION OF VENLAFAXINE HYDROCHLORIDE | ALEMBIC LIMITED (IN) | 2010-04-29 | — | — | WO | disclosed |
| CN-100364966-C | Process of synthesizing 1-[2-amino-1-(p-methoxylphenyl)-ethyl] cyclohexanol formate | SHANGHAI YABEN CHEMISTRY CO LT (CN) | 2008-01-30 | — | — | CN | disclosed |
| CN-1847219-A | Process of synthesizing 1-[2-amino-1-(p-methoxylphenyl)-ethyl] cyclohexanol formate | SHANGHAI YABEN CHEMISTRY CO LT (CN) | 2006-10-18 | — | — | CN | disclosed |
| WO-2006067808-A1 | AN IMPROVED PROCESS FOR PRODUCTION OF INTERMEDIATE OF ANTIDEPRESSANT AGENT | CALYX CHEMICALS & PHARMACEUTICALS PRIVATE LIMITED (IN) | 2006-06-29 | — | — | WO | disclosed |
| CN-1213994-C | Process for prepn. of phenethylamine derivatives | CIBA SC HOLDING AG (CH) | 2005-08-10 | — | — | CN | disclosed |
| CN-1481354-A | Process for prepn. of phenethylamine derivatives | �������⻯ѧƷ�ع�����˾ | 2004-03-10 | — | — | CN | disclosed |
| CN-1225356-A | Synthetic method of 1-[2-amino-1-(P-methoxybenzyl) ethyl] cyclohexanol | UNIV EAST CHINA SCIENCE & ENG (CN) | 1999-08-11 | — | — | CN | disclosed |