Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 5/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 5/20 | 0.43 |
| ▸ | ALOX5AP | P20292 | 5/20 | 0.43 |
| ▸ | FEN1 | P39748 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3350496 | 0.83 | HCRTR1 (0.43) | HCRTR1HCRTR2ALOX5APFEN1MEN1 | |
| SCHEMBL1398915 | 0.81 | HCRTR1 (0.47) | HCRTR1HCRTR2ALOX5APFEN1MEN1 | |
| SCHEMBL2635037 | 0.78 | HCRTR1 (0.43) | HCRTR1HCRTR2ALOX5APFEN1MEN1 | |
| SCHEMBL4311858 | 0.77 | HCRTR1 (0.47) | HCRTR1HCRTR2ALOX5APFEN1MEN1 | |
| SCHEMBL3345948 | 0.76 | HCRTR2 (0.38) | HCRTR1HCRTR2MEN1KMT2AALDH1A1 | |
| SCHEMBL3311253 | 0.76 | HCRTR1 (0.41) | HCRTR1HCRTR2ALOX5APFEN1MEN1 | |
| SCHEMBL1398919 | 0.75 | HCRTR1 (0.47) | HCRTR1HCRTR2MEN1KMT2ALMNA | |
| SCHEMBL2931084 | 0.75 | HCRTR2 (0.44) | HCRTR1HCRTR2ALOX5APFEN1MEN1 | |
| SCHEMBL3412528 | 0.75 | HCRTR2 (0.44) | HCRTR1HCRTR2ALOX5APFEN1MEN1 | |
| SCHEMBL3343763 | 0.74 | HCRTR1 (0.49) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010038200-A1 | OXAZOLIDINE COMPOUNDS AS OREXIN RECEPTOR ANTAGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2010-04-08 | — | — | WO | claimed |
| WO-2010038200-A1 | OXAZOLIDINE COMPOUNDS AS OREXIN RECEPTOR ANTAGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2010-04-08 | — | — | WO | disclosed |