Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.62 |
| ▸ | KCNQ3 | O43525 | 3/20 | 0.50 |
| ▸ | KCNQ2 | O43526 | 3/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.49 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.49 |
| ▸ | KCNQ4 | P56696 | 2/20 | 0.48 |
| ▸ | KCNQ5 | Q9NR82 | 2/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3346321 | 0.88 | KCNH2 (0.77) | KCNH2KCNQ3KCNQ2ATML3MBTL1 | |
| SCHEMBL3346230 | 0.85 | KCNQ3 (0.66) | KCNH2KCNQ3KCNQ2ROCK2KCNQ4 | |
| SCHEMBL3346676 | 0.84 | KCNQ3 (0.53) | KCNH2KCNQ3KCNQ2ATMROCK2 | |
| SCHEMBL3346599 | 0.82 | KCNH2 (0.68) | KCNH2KCNQ3KCNQ2ROCK2KCNQ4 | |
| SCHEMBL3350659 | 0.82 | KCNH2 (0.68) | KCNH2KCNQ3KCNQ2ROCK2KCNQ4 | |
| SCHEMBL13365111 | 0.82 | KCNH2 (0.68) | KCNH2KCNQ3KCNQ2ROCK2KCNQ4 | |
| SCHEMBL3346364 | 0.82 | KCNH2 (0.68) | KCNH2KCNQ3KCNQ2ROCK2KCNQ4 | |
| SCHEMBL3353009 | 0.81 | KCNH2 (0.67) | KCNH2KCNQ3KCNQ2ROCK2KCNQ4 | |
| SCHEMBL3346354 | 0.81 | KCNH2 (0.67) | KCNH2KCNQ3KCNQ2ROCK2KCNQ4 | |
| SCHEMBL3346485 | 0.81 | KCNH2 (0.63) | KCNH2KCNQ3KCNQ2KCNQ4KCNQ5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010059922-A1 | PYRROLIDINE CARBOXAMIDE COMPOUNDS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2010-05-27 | — | — | WO | claimed |