SCHEMBL335075

SCHEMBL335075

O=C(Cl)c1ccc2ccccc2n1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGAM O43451 1/20 0.68
CNR2 P34972 4/20 0.61
HDAC8 Q9BY41 1/20 0.61
RAB9A P51151 6/20 0.61
SMN1; SMN2 Q16637 5/20 0.61
NFKB1 P19838 3/20 0.61
NFKB2 Q00653 3/20 0.61
RELA Q04206 3/20 0.61
ALDH1A1 P00352 4/20 0.59
MAPT P10636 3/20 0.59
GAA P10253 1/20 0.59
KDM4E B2RXH2 3/20 0.56
NPC1 O15118 5/20 0.54
TP53 P04637 3/20 0.54
TSHR P16473 1/20 0.54
KDM4C Q9H3R0 1/20 0.53
MEN1 O00255 4/20 0.53
KMT2A Q03164 4/20 0.53
HPGD P15428 3/20 0.53
CYP1A2 P05177 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30835890 1.00 MGAM (0.68) MGAMCNR2HDAC8RAB9ASMN1; SMN2
Hydrochloric Acid SCHEMBL9524735 0.98 MGAM (0.66) MGAMCNR2HDAC8RAB9ASMN1; SMN2
Quinaldic Acid SCHEMBL6505548 0.93 MGAM (0.82) MGAMCNR2HDAC8RAB9ASMN1; SMN2
SCHEMBL1343443 0.83 CNR2 (0.78) MGAMCNR2HDAC8RAB9ASMN1; SMN2
Quinaldic Acid SCHEMBL29904839 0.82 MGAM (0.66) MGAMCNR2HDAC8RAB9ASMN1; SMN2
Quinaldic Acid SCHEMBL29350584 0.81 MGAM (1.00) MGAMCNR2HDAC8RAB9ASMN1; SMN2
Quinaldic Acid SCHEMBL1242670 0.81 MGAM (1.00) MGAMCNR2HDAC8RAB9ASMN1; SMN2
SCHEMBL2889584 0.81 MGAM (0.70) MGAMCNR2HDAC8RAB9ASMN1; SMN2
Quinaldic Acid SCHEMBL39024 0.81 MGAM (1.00) MGAMCNR2HDAC8RAB9ASMN1; SMN2
Quinaldic Acid SCHEMBL13571793 0.79 MGAM (0.96) MGAMCNR2HDAC8RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 188 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119431424-A Silicon oxime ester-containing photoinitiator, preparation method and application thereof 常州强力先端电子材料有限公司 2025-02-14 CN claimed
CN-117986232-A Oxime ester photoinitiator, preparation method and application thereof 常州强力电子新材料股份有限公司 2024-05-07 CN claimed
CN-117105897-A HNO donor compound and preparation method thereof 海南大学 2023-11-24 CN claimed
CN-117105826-A HNO-releasable compound and preparation method thereof 海南大学 2023-11-24 CN claimed
CN-112851547-A Fluorenoxime ester compound, preparation method thereof and photosensitive resin composition 常州强力先端电子材料有限公司 2021-05-28 CN claimed
CN-111417309-A Herbicidal combination UPL有限公司 2020-07-14 CN claimed
CN-111417308-A Herbicidal combination UPL有限公司 2020-07-14 CN claimed
CN-104230912-B Quinoline, Its Preparation Method And Use 中国科学院福建物质结构研究所 2017-06-06 CN claimed
EP-0669320-A2 Benzoylquinoiline derivatives NIHON BAYER AGROCHEM K.K. (JP) 1995-08-30 EP claimed
WO-1993014055-A1 PREPARATION OF 2,5-DICHLOROBENZOPHENONES MAXDEM INCORPORATED (US) 1993-07-22 WO claimed
EP-4713018-A1 TRANSFECTION COMPOSITIONS SUITABLE FOR PRODUCING A BIOLOGICAL PRODUCT PolyPlus Transfection (FR) 2026-03-25 EP disclosed
CN-116135889-B Oxime ester photoinitiator, photo-curing resin composition and application 常州强力电子新材料股份有限公司 2025-04-18 CN disclosed
WO-2024236194-A1 TRANSFECTION COMPOSITIONS SUITABLE FOR PRODUCING A BIOLOGICAL PRODUCT POLYPLUS TRANSFECTION (FR) 2024-11-21 WO disclosed
CN-118724866-A Oxime ester photoinitiator, photo-curing resin composition and application 常州强力先端电子材料有限公司 2024-10-01 CN disclosed
CN-117986231-A Oxime ester photoinitiator, preparation method and application thereof 常州强力电子新材料股份有限公司 2024-05-07 CN disclosed
US-4656174-A HYPOTENSIVE AGENTS PFIZER INC. (US) 1987-04-07 US disclosed
US-4634776-A ANALGESIC, ANTIRHEUMATIC, ANTIINFLAMMATORY STERLING DRUG, INC. (US) 1987-01-06 US disclosed
US-4581354-A ANALGESICS;ANTI-RHEUMATIC AND ANTI-INFLAMMATORY AGENTS STERLING DRUG INC. (US) 1986-04-08 US disclosed
EP-0171037-A2 3-Carbonyl-1-aminoalkyl-1H-indoles useful as analgesics and preparation thereof STERLING WINTHROP INC. (US) 1986-02-12 EP disclosed
US-3989685-A FROM PENICILLIN-1-OXIDE SHINOGI & CO., LTD. (JA) 1976-11-02 US disclosed