⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL137154 | 0.71 | — | — | |
| SCHEMBL102759 | 0.71 | — | — | |
| SCHEMBL483199 | 0.71 | — | — | |
| SCHEMBL9538013 | 0.64 | — | — | |
| SCHEMBL5639235 | 0.64 | — | — | |
| SCHEMBL8404072 | 0.64 | — | — | |
| SCHEMBL30832 | 0.64 | — | — | |
| SCHEMBL5639233 | 0.64 | — | — | |
| SCHEMBL23367978 | 0.64 | — | — | |
| SCHEMBL5909144 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117186013-A | Protein degradation agent with abietic acid as hydrophobic group, preparation method, pharmaceutical composition and application thereof | 南开大学 | 2023-12-08 | — | — | CN | disclosed |
| EP-3556759-B1 | HAPTENS OF PALIPERIDONE | JANSSEN PHARMACEUTICA NV (BE) | 2023-11-29 | — | — | EP | disclosed |
| US-11225527-B2 | Antibodies to paliperidone haptens and use thereof | JANSSEN PHARMACEUTICA NV (BE) | 2022-01-18 | — | — | US | disclosed |
| US-10913726-B2 | Centrally active and orally bioavailable antidotes for organophosphate exposure and methods for making and using them | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-02-09 | — | — | US | disclosed |
| US-10910634-B2 | Electroactive ionic liquids and surface-modified substrates containing them | UNIVERSITÉ PARIS CITÉ (FR) | 2021-02-02 | — | — | US | disclosed |
| EP-3453038-B1 | ELECTROACTIVE IONIC LIQUIDS AND SURFACE-MODIFIED SUBSTRATES CONTAINING THEM | CENTRE NAT RECH SCIENT (FR) | 2020-12-16 | — | — | EP | disclosed |
| US-10800749-B2 | Centrally active and orally bioavailable antidotes for organophosphate exposure and methods for making and using them | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-10-13 | — | — | US | disclosed |
| US-20190338047-A1 | Antibodies to Paliperidone Haptens and Use Thereof | JANSSEN PHARMACEUTICA NV (BE) | 2019-11-07 | — | — | US | disclosed |
| US-20190337911-A1 | CENTRALLY ACTIVE AND ORALLY BIOAVAILABLE ANTIDOTES FOR ORGANOPHOSPHATE EXPOSURE AND METHODS FOR MAKING AND USING THEM | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2019-11-07 | — | — | US | disclosed |
| EP-3556759-A1 | HAPTENS OF PALIPERIDONE | Janssen Pharmaceutica NV (BE) | 2019-10-23 | — | — | EP | disclosed |
| US-20060289833-A1 | Esters of phosphorus-oxygen acids, these esters comprising alkoxy groups, and their use as corrosion inhibitors and flameproofing agents | BASF ATKIENGESELLSCHAFT (DE) | 2006-12-28 | — | — | US | disclosed |
| US-20060156960-A1 | Use of phosphorus-oxygen acid esters containing alkoxy groups as corrosion inhibitors for reinforced concrete | SIKA TECHNOLOGY AG (CH) | 2006-07-20 | — | — | US | disclosed |
| CN-1784367-A | Use of phosphorus-oxygen acid esters containing alkoxy groups as corrosion inhibitors for reinforced concrete | SIKA TECHNOLOGY AG (CH) | 2006-06-07 | — | — | CN | disclosed |
| EP-1633365-A1 | MACROCYCLIC QUINAZOLINE DERIVATIVES AS ANTIPROLIFERATIVE AGENTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-03-15 | — | — | EP | disclosed |
| WO-2004105765-A1 | MACROCYCLIC QUINAZOLINE DERIVATIVES AS ANTIPROLIFERATIVE AGENTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2004-12-09 | — | — | WO | disclosed |
| EP-1083888-A1 | MULTIBINDING AGENTS THAT MODULATE PPARgamma AND RXR RECEPTORS | Advanced Medicine, Inc. (US) | 2001-03-21 | — | — | EP | disclosed |
| WO-1999063983-A9 | MULTIBINDING AGENTS THAT MODULATE PPARη AND RXR RECEPTORS | ADVANCED MEDICINE INC (US) | 2000-03-23 | — | — | WO | disclosed |
| WO-1999063983-A1 | MULTIBINDING AGENTS THAT MODULATE PPARη AND RXR RECEPTORS | ADVANCED MEDICINE, INC. (US) | 1999-12-16 | — | — | WO | disclosed |
| US-5073565-A | Atherosclerosis, anticholesterol | WARNER-LAMBERT COMPANY (US) | 1991-12-17 | — | — | US | disclosed |
| WO-1991017150-A1 | TETRAZOLE UREA AND THIOUREA ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1991-11-14 | — | — | WO | disclosed |