Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24779924 | 0.85 | KCNH2 (0.42) | MAPTLMNAALDH1A1GPR119KCNH2 | |
| SCHEMBL25210991 | 0.83 | USP30 (0.46) | MAPTGPR119DDB1CRBNHCAR1 | |
| SCHEMBL25338952 | 0.83 | NR1H2 (0.46) | MAPTALDH1A1NPC1RAB9AGPR119 | |
| SCHEMBL25904883 | 0.83 | GPR119 (0.40) | MAPTLMNAALDH1A1GPR119SMN1; SMN2 | |
| SCHEMBL30291070 | 0.83 | GPR119 (0.39) | MAPTLMNAALDH1A1GPR119KCNH2 | |
| SCHEMBL28872443 | 0.82 | KMT2A (0.44) | MAPTALDH1A1MEN1KMT2AGPR119 | |
| SCHEMBL20377783 | 0.82 | DDB1 (0.40) | MAPTLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL20606541 | 0.82 | IRAK4 (0.43) | — | |
| SCHEMBL30158059 | 0.81 | MAPT (0.44) | MAPTALDH1A1KMT2AGPR119DDB1 | |
| SCHEMBL20135591 | 0.81 | GPR119 (0.50) | GPR119DDB1CRBNHCAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |