Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 5/20 | 0.39 |
| ▸ | CASP3 | P42574 | 7/20 | 0.36 |
| ▸ | CASP7 | P55210 | 2/20 | 0.36 |
| ▸ | CASP2 | P42575 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.35 |
| ▸ | FER | P16591 | 1/20 | 0.35 |
| ▸ | LTK | P29376 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 1/20 | 0.35 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL28389634 | 0.98 | GSK3B (0.39) | GSK3BKDM4EALDH1A1GAAHPGD | |
| SCHEMBL1234203 | 0.95 | GSK3B (0.39) | GSK3BKDM4EALDH1A1GAAHPGD | |
| SCHEMBL9152783 | 0.94 | GSK3B (0.38) | GSK3BKDM4EALDH1A1GAAHPGD | |
| SCHEMBL9151570 | 0.94 | GSK3B (0.38) | GSK3BKDM4EALDH1A1GAAHPGD | |
| SCHEMBL31036258 | 0.94 | GSK3B (0.38) | GSK3BKDM4EALDH1A1GAAHPGD | |
| SCHEMBL133934 | 0.94 | GSK3B (0.38) | GSK3BKDM4EALDH1A1GAAHPGD | |
| SCHEMBL4909203 | 0.94 | GSK3B (0.38) | GSK3BKDM4EALDH1A1GAAHPGD | |
| SCHEMBL4026807 | 0.94 | GSK3B (0.38) | GSK3BKDM4EALDH1A1GAAHPGD | |
| SCHEMBL8938070 | 0.94 | GSK3B (0.38) | GSK3BKDM4EALDH1A1GAAHPGD | |
| SCHEMBL4206081 | 0.94 | GSK3B (0.38) | GSK3BKDM4EALDH1A1GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 499 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4724442-A1 | AGONISM-ANTAGONISM IN ENDOSOMAL TLRS BY MODULATING CHEMICAL FEATURES IN 8-OXOPURINE: PROCESS FOR PREPARATION AND APPLICATION THEREOF | Council of Scientific and Industrial Research (IN) | 2026-04-15 | — | — | EP | claimed |
| CN-113968809-B | Chemical synthesis method of melatonin | 太阳树(莆田)生物医药有限公司 | 2024-08-30 | — | — | CN | claimed |
| CN-113968809-A | Chemical synthesis method of melatonin | 太阳树(莆田)生物医药有限公司 | 2022-01-25 | — | — | CN | claimed |
| US-RE35631-E | Method of production of essentially pure melatonin and the method of solubilizing melatonin in water | IFLO S.A.S. (IT) | 1997-10-14 | — | — | US | claimed |
| EP-0330625-B1 | Total synthesis method for making an indole structure derivative product class, of the triptamine type, in particular, melatonin or N-acetyl-5-methoxytriptamine type, having a high purity degree and easily soluble, for therapeutic use against acquired immuno-deficiency syndromes | I F L O S A S DI GIORGIO E ALD (IT) | 1995-12-20 | — | — | EP | claimed |
| EP-0220409-B1 | GEM-DIHALO AND TETRAHALO-1,12-DIAMINO-4,9-DIAZA-DODECANES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1991-11-27 | — | — | EP | claimed |
| EP-0215319-B1 | GEM-DIHALO-1,8-DIAMINO-4-AZA-OCTANES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1991-10-16 | — | — | EP | claimed |
| US-4914240-A | PROTECTING DIHALO BUTANEDIOL, REACTING WITH POTASSIUM PHTHALIMINDE, DEPROTECTING; MULTISTEP | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-04-03 | — | — | US | claimed |
| EP-0330625-A2 | Total synthesis method for making an indole structure derivative product class, of the triptamine type, in particular, melatonin or N-acetyl-5-methoxytriptamine type, having a high purity degree and easily soluble, for therapeutic use against acquired immuno-deficiency syndromes | I.F.L.O. S.a.s. di Giorgio e Aldo Laguzzi (IT) | 1989-08-30 | — | — | EP | claimed |
| EP-0220409-A2 | Gem-dihalo and tetrahalo-1,12-diamino-4,9-diaza-dodecanes | MERRELL DOW PHARMACEUTICALS INC. (US) | 1987-05-06 | — | — | EP | claimed |
| EP-0215319-A2 | Gem-dihalo-1,8-diamino-4-aza-octanes | MERRELL DOW PHARMACEUTICALS INC. (US) | 1987-03-25 | — | — | EP | claimed |
| JP-7002741-A | — | — | None | — | — | JP | disclosed |
| JP-8100129-A | — | — | None | — | — | JP | disclosed |
| JP-2003680-A | — | — | None | — | — | JP | disclosed |
| EP-4724442-A1 | AGONISM-ANTAGONISM IN ENDOSOMAL TLRS BY MODULATING CHEMICAL FEATURES IN 8-OXOPURINE: PROCESS FOR PREPARATION AND APPLICATION THEREOF | Council of Scientific and Industrial Research (IN) | 2026-04-15 | — | — | EP | disclosed |
| US-4018931-A | INHIBITION OF H-2 HISTAMINE RECEPTORS | SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) | 1977-04-19 | — | — | US | disclosed |
| US-4013769-A | ANTIHISTAMINES | SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) | 1977-03-22 | — | — | US | disclosed |
| US-4000302-A | ANTIHISTAMINES | SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) | 1976-12-28 | — | — | US | disclosed |
| US-3950333-A | HISTAMINE INHIBITORS, OXYALKYL, THIOALKYL, AMINOALKYL DERIVATIVES | SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) | 1976-04-13 | — | — | US | disclosed |
| US-3950353-A | HISTAMINE INHIBITORS | SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) | 1976-04-13 | — | — | US | disclosed |