SCHEMBL33526642

SCHEMBL33526642

Cn1nc(F)c2c1cc(OC(F)F)c[n+]2[O-]

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SCN9A Q15858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL33526579 0.71 HRH4 (0.35) SCN9A
SCHEMBL14970148 0.63 ADORA2A (0.49) SCN9A
SCHEMBL33526541 0.63
SCHEMBL557901 0.62 SCN9A (0.57) SCN9A
SCHEMBL33527018 0.60 GRIN1 (0.34) SCN9A
SCHEMBL10272039 0.60 SCN9A (0.39) SCN9A
SCHEMBL10219969 0.60 SCN9A (0.39) SCN9A
SCHEMBL14752463 0.60 ADORA2A (0.49) SCN9A
SCHEMBL14737228 0.59 SYK (0.41) SCN9A
SCHEMBL23236538 0.58 GRIN1 (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260091048-A1 GIP RECEPTOR AGONIST COMPOUNDS LILLY CO ELI (US) 2026-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260091048-A1 GIP RECEPTOR AGONIST COMPOUNDS GIPR, GLP1R, GPR119 SCN9A 504/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.