⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7391309 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL335270 | 0.98 | ALOX15 (0.44) | — | |
| Hydrochloric Acid SCHEMBL7286569 | 0.98 | ALOX15 (0.44) | — | |
| Trifluoroacetic Acid SCHEMBL4085753 | 0.86 | ALOX15 (0.35) | — | |
| SCHEMBL6818831 | 0.81 | HCAR2 (0.38) | — | |
| SCHEMBL7879761 | 0.81 | GABRR1 (0.54) | — | |
| SCHEMBL4639637 | 0.81 | GABRR1 (0.54) | — | |
| SCHEMBL28212355 | 0.79 | GABRR1 (0.52) | — | |
| SCHEMBL28212354 | 0.79 | GABRR1 (0.52) | — | |
| SCHEMBL30360217 | 0.79 | GABRR1 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 197 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119677528-A | Compositions and methods for treating solid cancers | 埃欧艾米斯公司 | 2025-03-21 | — | — | CN | claimed |
| US-20040220264-A1 | Bioavailability and improved delivery of acidic pharmaceutical drugs | YU RUEY J | 2004-11-04 | — | — | US | claimed |
| EP-4616913-A2 | GCN2 INHIBITORS AND USES THEREOF | Merck Patent GmbH (DE) | 2025-09-17 | — | — | EP | disclosed |
| EP-3746075-B1 | GCN2 INHIBITORS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2025-09-03 | — | — | EP | disclosed |
| EP-2976400-B1 | ZUSAMMENSETZUNG, ENTHALTEND ALLOPHANATE | VENCOREX FRANCE (FR) | 2024-07-24 | — | — | EP | disclosed |
| US-12030875-B2 | EIF4E inhibitors and uses thereof | PIC Therapeutics, Inc. (US) | 2024-07-09 | — | — | US | disclosed |
| CN-118005640-A | GCN2 inhibitors and uses thereof | 默克专利股份有限公司 | 2024-05-10 | — | — | CN | disclosed |
| CN-111918651-B | GCN2 inhibitors and uses thereof | 默克专利股份有限公司 | 2024-01-30 | — | — | CN | disclosed |
| EP-3846793-B1 | EIF4E INHIBITORS AND USES THEREOF | PIC THERAPEUTICS INC (US) | 2024-01-24 | — | — | EP | disclosed |
| EP-3846793-B1 | EIF4E INHIBITORS AND USES THEREOF | PIC THERAPEUTICS INC (US) | 2024-01-24 | — | — | EP | disclosed |
| US-20220340577-A1 | GCN2 INHIBITORS AND USES THEREOF | VERTEX PHARMACEUTICALS INCORPORATED | 2022-10-27 | — | — | US | disclosed |
| US-5344837-A | Platelet aggregation inhibitors | G.D. SEARLE & CO. (US) | 1994-09-06 | — | — | US | disclosed |
| WO-1994017041-A1 | AMIDINOPHENYL SUBSTITUTED UREA, THIOUREA OR GUANIDINO DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1994-08-04 | — | — | WO | disclosed |
| US-5314902-A | Thioureas and guanidine compounds, anticoagulants | MONSANTO COMPANY (US) | 1994-05-24 | — | — | US | disclosed |
| WO-1994001396-A1 | PHENYL AMIDINE UREA DERIVATIVES AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1994-01-20 | — | — | WO | disclosed |
| US-5272162-A | Platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1993-12-21 | — | — | US | disclosed |
| US-5239113-A | Anticoagulants | MONSANTO COMPANY (US) | 1993-08-24 | — | — | US | disclosed |
| EP-0542708-A1 | Substituted B-amino acid derivatives useful as platelet aggregation inhibitors | MONSANTO COMPANY (US) | 1993-05-19 | — | — | EP | disclosed |
| WO-1993007867-A1 | SUBSTITUTED β-AMINO ACID DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1993-04-29 | — | — | WO | disclosed |
| US-4766110-A | INHIBITS ANGIOTENSIN CONVERTING ENZYME, HYPOTENSIVE AGENTS | RYAN JAMES W (US) | 1988-08-23 | — | — | US | disclosed |