SCHEMBL33528006

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10271520	0.82	FFAR1 (0.40)	HTR2AKDRROCK1LCKCSF1R
	SCHEMBL19724600	0.78	FFAR1 (0.37)	HTR2AKDRROCK1LCKCSF1R
	SCHEMBL2328937	0.78	PARP1 (0.47)	KDRROCK1LCKCSF1RFGFR1
	SCHEMBL3944570	0.77	KDR (0.38)	HTR2AKDRROCK1LCKCSF1R
	SCHEMBL31411355	0.76	HTR2A (0.55)	HTR2AKDRDYRK1AFFAR1GPR84
	SCHEMBL30248298	0.76	GAA (0.61)	KDRROCK1LCKCSF1RFGFR1
	SCHEMBL185907	0.76	GAA (0.61)	KDRROCK1LCKCSF1RFGFR1
	SCHEMBL3443437	0.72	CYP1A2 (0.43)	HTR2AKDRROCK1LCKCSF1R
	SCHEMBL1573886	0.72	GAA (0.43)	HTR2AKDRROCK1LCKCSF1R
	SCHEMBL11904474	0.72	KDR (0.40)	HTR2AKDRROCK1LCKCSF1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.