Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GALR3 | O60755 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL809764 | 0.87 | CYP1A2 (0.54) | CYP1A2CYP2D6CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL1087552 | 0.81 | GABRA1 (0.59) | CYP1A2CYP2D6CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL30962428 | 0.78 | CYP1A2 (0.57) | CYP1A2CYP2D6CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL27322 | 0.78 | CYP1A2 (0.57) | CYP1A2CYP2D6CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL1250152 | 0.77 | CYP1A2 (0.62) | CYP1A2CYP2D6CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL14599163 | 0.76 | CYP3A4 (0.51) | CYP1A2CYP2D6CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL7085860 | 0.75 | GABRA1 (0.42) | CYP1A2CYP2D6CYP2C9CYP2C19TSHR | |
| SCHEMBL11087878 | 0.75 | CYP3A4 (0.71) | CYP1A2CYP2C9CYP2C19CYP3A4TSHR | |
| SCHEMBL29824185 | 0.75 | CYP3A4 (0.71) | CYP1A2CYP2C9CYP2C19CYP3A4TSHR | |
| SCHEMBL3163975 | 0.75 | TSHR (0.45) | CYP1A2CYP2D6CYP2C9CYP2C19CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2172512-B1 | Granular stabilizer for polymer and production process thereof | SUMITOMO CHEMICAL CO (JP) | 2013-04-03 | — | — | EP | disclosed |
| EP-2172512-A1 | Granular stabilizer for polymer and production process thereof | Sumitomo Chemical Company, Limited (JP) | 2010-04-07 | — | — | EP | disclosed |