Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1712317 | 0.96 | POLB (0.54) | POLBTDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL20400819 | 0.82 | TDP1 (0.51) | POLBTDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL3622336 | 0.82 | POLB (0.57) | POLBTDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL15075637 | 0.82 | POLB (0.85) | POLBTDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL24218219 | 0.81 | POLB (0.57) | POLBTDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL24269953 | 0.79 | MAPT (0.54) | POLBTDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL12094229 | 0.79 | POLB (0.58) | POLBTDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL1712044 | 0.79 | KMT2A (0.60) | POLBTDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL12091517 | 0.78 | POLB (0.57) | POLBTDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL23397122 | 0.78 | LMNA (0.58) | POLBTDP1KMT2ASLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3082867-B1 | ISOXAZOLINE COMPOSITIONS AND USE THEREOF IN THE PREVENTION OR TREATMENT OF PARASITE INFESTATIONS IN ANIMALS | INTERVET INT BV (NL) | 2024-01-17 | — | — | EP | disclosed |
| EP-4306168-A2 | ISOXAZOLINE COMPOSITIONS AND USE THEREOF IN THE PREVENTION OR TREATMENT OF PARASITE INFESTATIONS IN ANIMALS | Intervet International B.V. (NL) | 2024-01-17 | — | — | EP | disclosed |
| EP-4076447-B1 | PARASITE CONTROL IN RUMINANTS | INTERVET INT BV (NL) | 2024-01-17 | — | — | EP | disclosed |
| EP-4153133-B1 | INJECTABLE PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | INTERVET INT BV (NL) | 2023-11-08 | — | — | EP | disclosed |
| EP-3878281-B1 | USE OF ISOXAZOLINE COMPOUNDS IN POULTRY | INTERVET INT BV (NL) | 2023-05-24 | — | — | EP | disclosed |
| EP-2833867-B2 | SOLID ORAL PHARMACEUTICAL COMPOSITIONS FOR ISOXAZOLINE COMPOUNDS | INTERVET INT BV (NL) | 2023-05-10 | — | — | EP | disclosed |
| WO-2022269042-A1 | PALATABLE VETERINARY COMPOSITIONS | INTERVET INTERNATIONAL B.V. (NL) | 2022-12-29 | — | — | WO | disclosed |
| WO-2022258797-A1 | TICK CONTROL METHODS | INTERVET INTERNATIONAL B.V. (NL) | 2022-12-15 | — | — | WO | disclosed |
| EP-4008329-A1 | ISOXAZOLINE COMPOUNDS FOR USE IN TREATING DEMODICOSIS | Intervet International B.V. (NL) | 2022-06-08 | — | — | EP | disclosed |
| EP-2658542-B1 | TOPICAL LOCALIZED ISOXAZOLINE FORMULATION | INTERVET INT BV (NL) | 2022-01-26 | — | — | EP | disclosed |
| US-20120225910-A1 | Substituted Heteroaryls | PFIZER INC. (US) | 2012-09-06 | — | — | US | disclosed |
| US-20120225910-A1 | Substituted Heteroaryls | PFIZER INC. (US) | 2012-09-06 | — | — | US | disclosed |
| US-20110230445-A1 | Substituted Heteroaryls | PFIZER INC | 2011-09-22 | — | — | US | disclosed |
| US-20110230445-A1 | Substituted Heteroaryls | PFIZER INC | 2011-09-22 | — | — | US | disclosed |
| US-7977367-B2 | Substituted imidazole propanamide glucokinase activators | PFIZER INC (US) | 2011-07-12 | — | — | US | disclosed |
| US-7977367-B2 | Substituted imidazole propanamide glucokinase activators | PFIZER INC (US) | 2011-07-12 | — | — | US | disclosed |
| WO-2010029461-A1 | HETEROARYLS AMIDE DERIVATIVES AND THEIR USE AS GLUCOKINASE ACTIVATORS | PFIZER INC. (US) | 2010-03-18 | — | — | WO | disclosed |
| WO-2010029461-A1 | HETEROARYLS AMIDE DERIVATIVES AND THEIR USE AS GLUCOKINASE ACTIVATORS | PFIZER INC. (US) | 2010-03-18 | — | — | WO | disclosed |
| US-20100063063-A1 | Substituted Heteroaryls | PFIZER INC | 2010-03-11 | — | — | US | disclosed |
| US-20100063063-A1 | Substituted Heteroaryls | PFIZER INC | 2010-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120225910-A1 | Substituted Heteroaryls | GCKR, GCK, GALK1 | POLB 3502/4885TDP1 2782/4885KMT2A 2365/4885 |
| US-20110230445-A1 | Substituted Heteroaryls | GCKR, GCK, GALK1 | POLB 3541/4885TDP1 2754/4885KMT2A 2175/4885 |
| US-20100063063-A1 | Substituted Heteroaryls | GCKR, GCK, GALK1 | POLB 3541/4885TDP1 2754/4885KMT2A 2175/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.