Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | F2 | P00734 | 1/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | DRD1 | P21728 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.54 |
| ▸ | DRD3 | P35462 | 1/20 | 0.54 |
| ▸ | KDR | P35968 | 1/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10979440 | 0.81 | MEN1 (0.60) | HTTKMT2ALMNAMEN1F2 | |
| SCHEMBL30668491 | 0.81 | MEN1 (0.60) | HTTKMT2ALMNAMEN1F2 | |
| SCHEMBL14910969 | 0.76 | KMT2A (0.54) | HTTKMT2ALMNAMEN1F2 | |
| SCHEMBL3352545 | 0.76 | ESR2 (0.38) | EGFR | |
| SCHEMBL14908778 | 0.76 | HTT (0.54) | HTTKMT2ALMNAMEN1F2 | |
| SCHEMBL25214404 | 0.76 | HTT (0.54) | HTTKMT2ALMNAMEN1F2 | |
| SCHEMBL16070947 | 0.76 | CYP1A2 (0.57) | HTTKMT2ALMNAMEN1F2 | |
| SCHEMBL8169341 | 0.72 | CYP1A2 (0.57) | ACHEKDREGFRHTR3AKDM4E | |
| SCHEMBL3576640 | 0.72 | EGFR (0.49) | HTTKMT2ALMNAMEN1F2 | |
| SCHEMBL21689072 | 0.72 | HPGDS (0.59) | HTTKMT2ALMNAMEN1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012002577-A1 | NOVEL NICOTINAMIDE DERIVATIVES OR SALTS THEREOF | 富士フイルム株式会社 (JP) | 2012-01-05 | — | — | WO | disclosed |