Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UCHL1 | P09936 | 6/20 | 0.54 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.37 |
| ▸ | GHSR | Q92847 | 3/20 | 0.36 |
| ▸ | IDO1 | P14902 | 3/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL33530699 | 0.90 | UCHL1 (0.53) | UCHL1NR1H2USP30NR1H3GHSR | |
| SCHEMBL33532197 | 0.88 | UCHL1 (0.51) | UCHL1NR1H2USP30NR1H3GHSR | |
| SCHEMBL11929927 | 0.86 | UCHL1 (0.42) | UCHL1GHSRDDB1CRBN | |
| SCHEMBL33531957 | 0.84 | UCHL1 (0.41) | UCHL1NR1H2USP30GHSRIDO1 | |
| SCHEMBL33532252 | 0.84 | UCHL1 (0.40) | UCHL1NR1H2USP30GHSRIDO1 | |
| SCHEMBL17681690 | 0.83 | UCHL1 (0.55) | UCHL1NR1H2USP30NR1H3DDB1 | |
| SCHEMBL29608082 | 0.83 | UCHL1 (0.55) | UCHL1NR1H2USP30NR1H3DDB1 | |
| SCHEMBL17681742 | 0.83 | UCHL1 (0.55) | UCHL1NR1H2USP30NR1H3DDB1 | |
| SCHEMBL28600766 | 0.83 | UCHL1 (0.55) | UCHL1NR1H2USP30NR1H3DDB1 | |
| SCHEMBL29607370 | 0.83 | UCHL1 (0.55) | UCHL1NR1H2USP30NR1H3DDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260092061-A1 | COMPOUNDS FOR TARGETED PROTEIN DEGRADATION | AMPHISTA THERAPEUTICS LTD (GB) | 2026-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260092061-A1 | COMPOUNDS FOR TARGETED PROTEIN DEGRADATION | BCL9L, RBBP9, BRD9 | UCHL1 261/4885NR1H2 1553/4885USP30 447/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.