Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 5/20 | 0.68 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | TLR2 | O60603 | 1/20 | 0.50 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13365063 | 1.00 | MC4R (0.68) | MC4RKCNH2SMN1; SMN2ALDH1A1TLR2 | |
| SCHEMBL13364991 | 0.91 | MC4R (0.77) | MC4RKCNH2ALDH1A1TLR2TLR1 | |
| SCHEMBL23951303 | 0.91 | MC4R (0.77) | MC4RKCNH2ALDH1A1TLR2TLR1 | |
| SCHEMBL23951395 | 0.91 | MC4R (0.77) | MC4RKCNH2ALDH1A1TLR2TLR1 | |
| Hydrochloric Acid SCHEMBL23923790 | 0.89 | MC4R (0.75) | MC4RKCNH2ALDH1A1TLR2TLR1 | |
| SCHEMBL2226816 | 0.87 | MC4R (0.68) | MC4RKCNH2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL13365061 | 0.86 | KCNH2 (0.79) | MC4RKCNH2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL3350446 | 0.86 | KCNH2 (0.79) | MC4RKCNH2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL13364990 | 0.84 | KCNH2 (0.69) | MC4RKCNH2SMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL23951255 | 0.82 | MC4R (0.63) | MC4RKCNH2SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010059922-A1 | PYRROLIDINE CARBOXAMIDE COMPOUNDS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2010-05-27 | — | — | WO | claimed |