SCHEMBL33532547

SCHEMBL33532547

N#Cc1ccc(-c2cncc3c2CCN3C(=O)c2ccc(C(=O)O)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ SLC22A12 Q96S37 1/20 0.50
▸ USP30 Q70CQ3 2/20 0.46
▸ UCHL1 P09936 1/20 0.46
▸ MAP4K4 O95819 1/20 0.45
▸ CYP11B2 P19099 7/20 0.44
▸ CYP11B1 P15538 6/20 0.44
▸ PDCD1 Q15116 8/20 0.43
▸ CD274 Q9NZQ7 8/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30774625 0.96 USP30 (0.49) SLC22A12USP30UCHL1CYP11B2CYP11B1
SCHEMBL30774475 0.90 USP30 (0.46) SLC22A12USP30UCHL1CYP11B2CYP11B1
SCHEMBL30774426 0.90 CYP11B2 (0.48) SLC22A12USP30UCHL1CYP11B2CYP11B1
SCHEMBL30774532 0.90 USP30 (0.46) SLC22A12USP30UCHL1CYP11B2CYP11B1
SCHEMBL30774411 0.89 KDM1A (0.47) SLC22A12USP30UCHL1CYP11B2CYP11B1
SCHEMBL30774401 0.88 CYP11B2 (0.44) SLC22A12USP30UCHL1CYP11B2CYP11B1
SCHEMBL30774399 0.88 CYP11B2 (0.51) USP30UCHL1CYP11B2CYP11B1PDCD1
SCHEMBL31635535 0.88 PDCD1 (0.44) USP30UCHL1CYP11B2CYP11B1PDCD1
SCHEMBL30774430 0.88 PDCD1 (0.44) USP30UCHL1CYP11B2CYP11B1PDCD1
SCHEMBL30774528 0.87 USP30 (0.43) SLC22A12USP30UCHL1CYP11B2CYP11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260092074-A1 Annelated Pyridines as Steroidogenesis Inhibitors, Preparation Method and Use Thereof GUANGZHOU VINNOCENT PHARMACEUTICAL LTD (CN) 2026-04-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260092074-A1 Annelated Pyridines as Steroidogenesis Inhibitors, Preparation Method and Use Thereof STS, NR5A1, CYP21A2 SLC22A12 3869/4885USP30 728/4885UCHL1 1728/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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