Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.47 |
| ▸ | ACHE | P22303 | 5/20 | 0.43 |
| ▸ | BCHE | P06276 | 3/20 | 0.43 |
| ▸ | AGXT | P21549 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL975422 | 0.83 | IDO1 (0.48) | IDO1ACHEBCHEAGXTRAB9A | |
| SCHEMBL11988887 | 0.82 | IDO1 (0.44) | IDO1ACHEBCHEAGXTRAB9A | |
| SCHEMBL14899720 | 0.79 | APP (0.52) | IDO1CYP1A2 | |
| SCHEMBL14899725 | 0.79 | TDP1 (0.44) | IDO1RAB9ATDP1ALDH1A1MAPT | |
| SCHEMBL546541 | 0.78 | CYP1A2 (0.42) | IDO1CYP1A2TAAR1TDP1ALDH1A1 | |
| SCHEMBL28430892 | 0.75 | IDO1 (0.52) | IDO1ACHEBCHEAGXTRAB9A | |
| SCHEMBL18531376 | 0.74 | BCHE (0.45) | IDO1ACHEBCHEAGXTRAB9A | |
| SCHEMBL915196 | 0.74 | IDO1 (0.54) | IDO1ACHERAB9ACYP1A2CYP2A6 | |
| SCHEMBL2802287 | 0.74 | IDO1 (0.54) | IDO1ACHEBCHEAGXTRAB9A | |
| Methylene Chloride SCHEMBL28192144 | 0.73 | CYP1A2 (0.38) | IDO1CYP1A2TAAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190047968-A1 | 6-ACYL-1,2,4-TRIAZINE-3,5-DIONE DERIVATIVE AND HERBICIDES | FMC CORP (US) | 2019-02-14 | — | — | US | disclosed |
| US-20170129861-A1 | 6-ACYL-1,2,4-TRIAZINE-3,5-DIONE DERIVATIVE AND HERBICIDES | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2017-05-11 | — | — | US | disclosed |
| US-9573909-B2 | 6-acyl-1,2,4-triazine-3,5-dione derivative and herbicides | FMC CORPORATION (US) | 2017-02-21 | — | — | US | disclosed |
| US-8334236-B2 | Ring-fused 2-pyridone derivatives and herbicides | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2012-12-18 | — | — | US | disclosed |
| WO-2012002096-A1 | 6-ACYL-1,2,4-TRIAZINE-3,5-DIONE DERIVATIVE AND HERBICIDES | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2012-01-05 | — | — | WO | disclosed |
| US-20110287937-A1 | RING-FUSED 2-PYRIDONE DERIVATIVES AND HERBICIDES | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2011-11-24 | — | — | US | disclosed |
| WO-2010089993-A1 | RING-FUSED 2-PYRIDONE DERIVATIVES AND HERBICIDES | クミアイ化学工業株式会社 (JP) | 2010-08-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110287937-A1 | RING-FUSED 2-PYRIDONE DERIVATIVES AND HERBICIDES | CBR3, CBR1, CHRM1 | IDO1 1015/4885ACHE 498/4885BCHE 1276/4885 |
| US-20170129861-A1 | 6-ACYL-1,2,4-TRIAZINE-3,5-DIONE DERIVATIVE AND HERBICIDES | DDT, AADAC, DAZAP1 | IDO1 258/4885ACHE 337/4885BCHE 853/4885 |
| US-20190047968-A1 | 6-ACYL-1,2,4-TRIAZINE-3,5-DIONE DERIVATIVE AND HERBICIDES | DDT, AADAC, DAZAP1 | IDO1 258/4885ACHE 337/4885BCHE 853/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.