SCHEMBL3354078

SCHEMBL3354078

O=C(NC[C@H]1CN(c2ccccc2S(=O)(=O)N2CCOCC2)C(=O)O1)c1ccc(Cl)s1

nearest known ligand 0.75

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.75
F2 P00734 2/20 0.61
ABCB11 O95342 1/20 0.61
ST14 Q9Y5Y6 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3354082 1.00 F10 (0.75) F10F2ABCB11ST14
SCHEMBL79703 0.85 F10 (0.87) F10F2ABCB11ST14
SCHEMBL79715 0.81 F10 (1.00) F10F2ABCB11ST14
SCHEMBL76791 0.80 F10 (1.00) F10F2ABCB11ST14
SCHEMBL7247311 0.80 F10 (1.00) F10F2ABCB11ST14
SCHEMBL24177659 0.78 F10 (1.00) F10F2ABCB11ST14
SCHEMBL13698655 0.78 F10 (1.00) F10F2ABCB11ST14
SCHEMBL77589 0.78 F10 (1.00) F10F2ABCB11ST14
SCHEMBL77202 0.78 F10 (1.00) F10F2ABCB11ST14
SCHEMBL3521124 0.78 F10 (1.00) F10F2ABCB11ST14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100120718-A1 COMBINATION THERAPY OF SUBSTITUTED OXAZOLIDINONES BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2010-05-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100120718-A1 COMBINATION THERAPY OF SUBSTITUTED OXAZOLIDINONES P2RY12, P2RY11, P2RY1 F10 1174/4885F2 398/4885ABCB11 255/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.