Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | HTR6 | P50406 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3358317 | 0.85 | SLC6A4 (0.64) | SLC6A4HTR6MAPT | |
| SCHEMBL17495520 | 0.83 | SLC6A4 (0.49) | SLC6A4HTR6MAPTMEN1KMT2A | |
| SCHEMBL3387401 | 0.83 | SLC6A4 (0.49) | SLC6A4HTR6MAPTMEN1KMT2A | |
| SCHEMBL3354832 | 0.82 | SLC6A4 (0.48) | SLC6A4HTR6MAPTMEN1KMT2A | |
| SCHEMBL3353186 | 0.81 | SLC6A4 (0.47) | SLC6A4HTR6MAPTKMT2AALDH1A1 | |
| SCHEMBL17495514 | 0.81 | SLC6A4 (0.47) | SLC6A4HTR6MAPTSCN9A | |
| SCHEMBL17495516 | 0.81 | SLC6A4 (0.47) | SLC6A4HTR6MAPTSCN9A | |
| SCHEMBL3352090 | 0.79 | SLC6A4 (0.46) | SLC6A4HTR6MAPTMEN1KMT2A | |
| SCHEMBL26630395 | 0.78 | HTR6 (0.46) | SLC6A4HTR6MAPTMEN1KMT2A | |
| SCHEMBL3358160 | 0.77 | SLC6A4 (0.60) | SLC6A4HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |