Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 15/20 | 0.89 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CALCA | P06881 | 5/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3354566 | 1.00 | CALCRL (0.89) | CALCRLCYP3A4CALCA | |
| SCHEMBL3358046 | 0.98 | CALCRL (0.88) | CALCRLCYP3A4CALCA | |
| SCHEMBL3358053 | 0.98 | CALCRL (0.88) | CALCRLCYP3A4CALCA | |
| SCHEMBL3354196 | 0.94 | CALCRL (0.83) | CALCRLCYP3A4 | |
| SCHEMBL13204027 | 0.94 | CALCRL (0.83) | CALCRLCYP3A4 | |
| SCHEMBL2981927 | 0.94 | CALCRL (1.00) | CALCRLCALCA | |
| SCHEMBL2971778 | 0.94 | CALCRL (1.00) | CALCRLCALCA | |
| SCHEMBL3355393 | 0.94 | CALCRL (0.78) | CALCRLCYP3A4CALCA | |
| SCHEMBL3355402 | 0.94 | CALCRL (0.78) | CALCRLCYP3A4CALCA | |
| SCHEMBL3353709 | 0.92 | CALCRL (0.77) | CALCRLCYP3A4CALCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7696195-B2 | Selected CGRP-antagonists, process for preparing them and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-04-13 | — | — | US | disclosed |
| US-20050256099-A1 | Selected CGRP-antagonists, process for preparing them and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050256099-A1 | Selected CGRP-antagonists, process for preparing them and their use as pharmaceutical compositions | CALCRL, CALCR, CALCA | CALCRL 1/4885CYP3A4 1001/4885CALCA 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.