Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 3/20 | 0.67 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.67 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.67 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.48 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.48 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MME | P08473 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3354732 | 1.00 | SLC1A3 (0.67) | SLC1A3SLC1A2SLC1A1KCNA5ADAM17 | |
| SCHEMBL7141895 | 0.83 | SLC1A3 (0.50) | SLC1A3SLC1A2SLC1A1KCNA5ADAM17 | |
| SCHEMBL7141899 | 0.83 | SLC1A3 (0.50) | SLC1A3SLC1A2SLC1A1KCNA5ADAM17 | |
| SCHEMBL4140520 | 0.83 | EDNRA (0.50) | SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL4140524 | 0.83 | EDNRA (0.50) | SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL5587391 | 0.83 | EDNRA (0.50) | SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL7137507 | 0.83 | SLC1A3 (0.49) | SLC1A3SLC1A2SLC1A1KCNA5ADAM17 | |
| SCHEMBL7137510 | 0.83 | SLC1A3 (0.49) | SLC1A3SLC1A2SLC1A1KCNA5ADAM17 | |
| SCHEMBL5587395 | 0.82 | SLC1A3 (0.48) | SLC1A3SLC1A2SLC1A1ADAMTS4MMP13 | |
| SCHEMBL20025843 | 0.82 | SLC1A3 (0.55) | SLC1A3SLC1A2SLC1A1KCNA5SLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0783489-A1 | ALDEHYDE DERIVATIVES AS UPSTEINE PROTEASE INHIBITORS | Takeda Chemical Industries, Ltd. (JP) | 1997-07-16 | — | — | EP | claimed |
| WO-1996010014-A1 | ALDEHYDE DERIVATIVES AS UPSTEINE PROTEASE INHIBITORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-04-04 | — | — | WO | claimed |
| WO-2010033658-A2 | CATHEPSIN L PROTEOLYTICALLY PROCESSES HISTONE H3 DURING MOUSE EMBROYONIC STEM CELL DIFFERENTIATION | THE ROCKEFELLER UNIVERSITY (US) | 2010-03-25 | — | — | WO | disclosed |
| EP-0783489-A1 | ALDEHYDE DERIVATIVES AS UPSTEINE PROTEASE INHIBITORS | Takeda Chemical Industries, Ltd. (JP) | 1997-07-16 | — | — | EP | disclosed |
| WO-1996010014-A1 | ALDEHYDE DERIVATIVES AS UPSTEINE PROTEASE INHIBITORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-04-04 | — | — | WO | disclosed |