Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | CMA1 | P23946 | 2/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6451102 | 0.83 | HSD17B10 (0.60) | HSD17B10ALOX15TSHRGLAKDM4E | |
| SCHEMBL31481214 | 0.81 | HSD17B10 (0.65) | HSD17B10ALOX15TSHRGLAKDM4E | |
| SCHEMBL22061005 | 0.81 | HSD17B10 (0.57) | HSD17B10ALOX15TSHRGLAKDM4E | |
| SCHEMBL14631512 | 0.79 | HSD17B10 (0.67) | HSD17B10ALOX15TSHRGLAKDM4E | |
| SCHEMBL3905353 | 0.79 | HSD17B10 (0.67) | HSD17B10ALOX15TSHRGLAKDM4E | |
| SCHEMBL19236720 | 0.79 | HSD17B10 (0.55) | HSD17B10ALOX15TSHRGLAKDM4E | |
| SCHEMBL3354784 | 0.78 | ELANE (0.42) | HSD17B10KDM4E | |
| SCHEMBL3354341 | 0.78 | HSD17B10 (0.65) | HSD17B10ALOX15GLAKDM4EHPGD | |
| SCHEMBL28726087 | 0.78 | HSD17B10 (0.65) | HSD17B10ALOX15TSHRGLAKDM4E | |
| SCHEMBL8426442 | 0.78 | CNR1 (0.55) | HSD17B10ALOX15KDM4EAKR1B1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010067233-A1 | 1,2,4 TRIAZOLO [4, 3 -A] [1,5] BENZODIAZEPIN-5 (6H) -ONES AS AGONISTS OF THE CHOLECYSTOKININ-1 RECEPTOR (CCK-IR) | PFIZER INC. (US) | 2010-06-17 | — | — | WO | disclosed |