Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | CMA1 | P23946 | 2/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3354746 | 0.83 | HSD17B10 (0.61) | HSD17B10ALOX15TSHRGLAKDM4E | |
| SCHEMBL3426837 | 0.80 | SLC16A3 (0.55) | HSD17B10ALOX15KDM4EHPGDALDH1A1 | |
| SCHEMBL22061005 | 0.79 | HSD17B10 (0.57) | HSD17B10ALOX15TSHRGLAKDM4E | |
| SCHEMBL3905353 | 0.78 | HSD17B10 (0.67) | HSD17B10ALOX15TSHRGLAKDM4E | |
| SCHEMBL14631512 | 0.78 | HSD17B10 (0.67) | HSD17B10ALOX15TSHRGLAKDM4E | |
| SCHEMBL19236720 | 0.77 | HSD17B10 (0.55) | HSD17B10ALOX15TSHRGLAKDM4E | |
| SCHEMBL31481214 | 0.76 | HSD17B10 (0.65) | HSD17B10ALOX15TSHRGLAKDM4E | |
| SCHEMBL3354341 | 0.76 | HSD17B10 (0.65) | HSD17B10ALOX15GLAKDM4EHPGD | |
| SCHEMBL28726087 | 0.76 | HSD17B10 (0.65) | HSD17B10ALOX15TSHRGLAKDM4E | |
| SCHEMBL13281112 | 0.76 | TSHR (0.61) | HSD17B10ALOX15TSHRCMA1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012065062-A1 | NOVEL ANTIVIRAL COMPOUNDS | PHARMARESOURCES(SHANGHAI)CO., LTD. (CN) | 2012-05-18 | — | — | WO | disclosed |