Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 3/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15774342 | 0.91 | PTGER4 (0.65) | PTGER4ALOX15KCNH2HRH3MEN1 | |
| SCHEMBL3416308 | 0.89 | ALDH1A1 (0.54) | MEN1KMT2AGAAGLAMAPT | |
| SCHEMBL18889172 | 0.86 | KCNH2 (0.47) | PTGER4ALOX15KCNH2HRH3MEN1 | |
| SCHEMBL13537225 | 0.84 | KCNH2 (0.46) | PTGER4KCNH2HRH3MEN1KMT2A | |
| SCHEMBL13537227 | 0.83 | KCNH2 (0.45) | PTGER4KCNH2HRH3MEN1KMT2A | |
| SCHEMBL3349981 | 0.82 | MAPT (0.59) | PTGER4KCNH2HRH3MEN1KMT2A | |
| SCHEMBL15774705 | 0.81 | PTGER4 (0.61) | PTGER4ALOX15MEN1KMT2AGAA | |
| SCHEMBL15774548 | 0.80 | ALDH1A1 (0.72) | PTGER4KCNH2KMT2AMAPTALDH1A1 | |
| SCHEMBL13497806 | 0.80 | PTGER4 (0.58) | PTGER4ALOX15KMT2AGAAMAPT | |
| SCHEMBL23286940 | 0.79 | ALDH1A1 (0.54) | MEN1KMT2AGLAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |