Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 6/20 | 0.60 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.60 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 4/20 | 0.44 |
| ▸ | CA2 | P00918 | 4/20 | 0.44 |
| ▸ | CA4 | P22748 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4243872 | 0.90 | PTGS2 (0.61) | PTGS2PTGS1MALT1 | |
| SCHEMBL4245103 | 0.89 | PTGS2 (0.60) | PTGS2PTGS1CA1CA2CA4 | |
| SCHEMBL4026247 | 0.88 | PTGS1 (0.76) | PTGS2PTGS1MALT1L3MBTL1 | |
| SCHEMBL3358808 | 0.87 | PTGS2 (0.55) | PTGS2PTGS1MALT1L3MBTL1PTPN11 | |
| SCHEMBL4245198 | 0.81 | PTGS2 (0.57) | PTGS2PTGS1MALT1CA1CA2 | |
| SCHEMBL3353074 | 0.79 | PTGS2 (0.58) | PTGS2PTGS1MALT1CA1CA2 | |
| SCHEMBL3355654 | 0.79 | PTGS2 (0.77) | PTGS2PTGS1MALT1L3MBTL1CA1 | |
| SCHEMBL4032188 | 0.78 | PTGS1 (0.72) | PTGS2PTGS1MALT1L3MBTL1 | |
| SCHEMBL4248349 | 0.78 | PTGS2 (0.75) | PTGS2PTGS1CA1CA2CA4 | |
| SCHEMBL6132198 | 0.77 | PTGS2 (0.62) | PTGS2PTGS1MALT1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4532283-B2 | — | — | 2010-08-25 | — | — | JP | claimed |
| EP-1565447-A4 | 1,2,4-TRIAZOLE DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | CJ CORP (KR) | 2005-11-16 | — | — | EP | claimed |
| EP-1565447-A1 | 1,2,4-TRIAZOLE DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | CJ Corporation (KR) | 2005-08-24 | — | — | EP | claimed |
| WO-2004048347-A1 | 1,2,4-TRIAZOLE DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | CJ CORPORATION (KR) | 2004-06-10 | — | — | WO | claimed |
| EP-1565447-A4 | 1,2,4-TRIAZOLE DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | CJ CORP (KR) | 2005-11-16 | — | — | EP | disclosed |
| EP-1565447-A1 | 1,2,4-TRIAZOLE DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | CJ Corporation (KR) | 2005-08-24 | — | — | EP | disclosed |
| WO-2004048347-A1 | 1,2,4-TRIAZOLE DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | CJ CORPORATION (KR) | 2004-06-10 | — | — | WO | disclosed |