SCHEMBL3356854

SCHEMBL3356854

CCOC(=O)C(=CN)CC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 2/20 0.43
GLO1 Q04760 1/20 0.43
ALOX15 P16050 1/20 0.42
SOAT1 P35610 1/20 0.42
ALDH1A1 P00352 5/20 0.42
TSHR P16473 1/20 0.42
LMNA P02545 2/20 0.39
HSD17B10 Q99714 1/20 0.39
CYP2D6 P10635 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
MGAM O43451 1/20 0.37
GAA P10253 1/20 0.37
SI P14410 1/20 0.37
MGAM2 Q2M2H8 1/20 0.37
EGLN1 Q9GZT9 1/20 0.36
CYP2C9 P11712 2/20 0.36
HCAR2 Q8TDS4 1/20 0.35
MAPT P10636 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16089862 1.00 NPSR1 (0.43) NPSR1GLO1ALOX15SOAT1ALDH1A1
SCHEMBL10621641 1.00 NPSR1 (0.43) NPSR1GLO1ALOX15SOAT1ALDH1A1
SCHEMBL3358511 0.83 NPSR1 (0.41) NPSR1GLO1ALOX15SOAT1ALDH1A1
SCHEMBL2951936 0.83 HCAR2 (0.39) ALDH1A1TSHRLMNASMN1; SMN2GAA
SCHEMBL7601504 0.81 NPSR1 (0.46) NPSR1GLO1ALOX15SOAT1ALDH1A1
SCHEMBL7600152 0.81 NPSR1 (0.46) NPSR1GLO1ALOX15SOAT1ALDH1A1
SCHEMBL3355797 0.79 FAAH (0.45) NPSR1GLO1ALOX15ALDH1A1TSHR
SCHEMBL14719757 0.79 TSHR (0.41) ALDH1A1TSHRHSD17B10SMN1; SMN2MEN1
SCHEMBL4351917 0.79 ATM (0.48) NPSR1ALDH1A1TSHRLMNAHSD17B10
SCHEMBL15641281 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114672267-B Adhesive film, optical member including the same, and optical display including the same 三星SDI株式会社 2024-03-12 CN disclosed
CN-116724095-A Adhesive film, optical member including the same, and optical display device including the same 三星SDI株式会社 2023-09-08 CN disclosed
EP-4213980-A1 AMINE MODIFIED POLYSACCHARIDE URETHANE/UREA MICROCAPSULES Encapsys, LLC (US) 2023-07-26 EP disclosed
WO-2022061103-A1 AMINE MODIFIED POLYSACCHARIDE URETHANE/UREA MICROCAPSULES ENCAPSYS, LLC (US) 2022-03-24 WO disclosed
US-20200392271-A1 ASSOCIATIVE POLYMER STRUCTURES AND METHODS OF USE THEREOF RHODIA OPERATIONS (FR) 2020-12-17 US disclosed
US-9249179-B2 Galactose cluster-pharmacokinetic modulator targeting moiety for siRNA Arrowhead Madison Inc. (US) 2016-02-02 US disclosed
US-8993112-B2 Polymeric particles BASF SE (DE) 2015-03-31 US disclosed
US-20120157509-A1 GALACTOSE CLUSTER-PHARMACOKINETIC MODULATOR TARGETING MOIETY FOR siRNA ARROWHEAD RESEARCH CORPORATION 2012-06-21 US disclosed
EP-1756184-B1 POLYMERIC PARTICLES BASF SE (DE) 2010-01-13 EP disclosed
US-20070255008-A1 Polymeric Particles CIBA CORPORATION 2007-11-01 US disclosed
EP-1756184-A1 POLYMERIC PARTICLES Ciba Specialty Chemicals Holding Inc. (CH) 2007-02-28 EP disclosed
WO-2005123796-A1 POLYMERIC PARTICLES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2005-12-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120157509-A1 GALACTOSE CLUSTER-PHARMACOKINETIC MODULATOR TARGETING MOIETY FOR siRNA GALK1, GALE, GALNT6 NPSR1 1507/4885GLO1 366/4885ALOX15 3579/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.