Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | LDHA | P00338 | 1/20 | 0.30 |
| ▸ | LDHB | P07195 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4855321 | 1.00 | TDP1 (0.35) | TDP1FFAR3ALDH1A1ALOX15LMNA | |
| SCHEMBL1831176 | 0.84 | TDP1 (0.41) | TDP1FFAR3ALDH1A1ALOX15LMNA | |
| SCHEMBL8688580 | 0.84 | TDP1 (0.41) | TDP1FFAR3ALDH1A1ALOX15LMNA | |
| SCHEMBL1831174 | 0.84 | TDP1 (0.41) | TDP1FFAR3ALDH1A1ALOX15LMNA | |
| SCHEMBL3357465 | 0.81 | ALDH1A1 (0.40) | TDP1FFAR3ALDH1A1 | |
| SCHEMBL4861546 | 0.81 | ALDH1A1 (0.40) | TDP1FFAR3ALDH1A1 | |
| SCHEMBL2636263 | 0.80 | GRIK1 (0.40) | TDP1FFAR3ALDH1A1ALOX15LMNA | |
| SCHEMBL5596730 | 0.80 | GRIK1 (0.40) | TDP1FFAR3ALDH1A1ALOX15LMNA | |
| SCHEMBL5253704 | 0.79 | — | — | |
| SCHEMBL8081484 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8993112-B2 | Polymeric particles | BASF SE (DE) | 2015-03-31 | — | — | US | disclosed |
| EP-1756184-B1 | POLYMERIC PARTICLES | BASF SE (DE) | 2010-01-13 | — | — | EP | disclosed |
| US-20070255008-A1 | Polymeric Particles | CIBA CORPORATION | 2007-11-01 | — | — | US | disclosed |
| EP-1756184-A1 | POLYMERIC PARTICLES | Ciba Specialty Chemicals Holding Inc. (CH) | 2007-02-28 | — | — | EP | disclosed |
| WO-2005123796-A1 | POLYMERIC PARTICLES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2005-12-29 | — | — | WO | disclosed |