⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7030344 | 0.75 | — | — | |
| SCHEMBL7030343 | 0.75 | — | — | |
| SCHEMBL1991070 | 0.72 | ALDH1A1 (0.38) | — | |
| SCHEMBL5125793 | 0.69 | — | — | |
| SCHEMBL23624 | 0.69 | — | — | |
| SCHEMBL1986601 | 0.69 | — | — | |
| SCHEMBL6895262 | 0.69 | — | — | |
| SCHEMBL9295954 | 0.67 | — | — | |
| SCHEMBL6478456 | 0.67 | — | — | |
| SCHEMBL6547866 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7709465-B2 | Phosphorous containing compounds including triphenylmethylphosphonate esters for the treatment of melanoma and other cancers | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2010-05-04 | — | — | US | disclosed |
| EP-2034828-A2 | PHOSPHOROUS CONTAINING COMPOUNDS INCLUDING TRIPHENYLMETHYLPHOSPHONATE ESTERS FOR THE TREATMENT OF MELANOMA AND OTHER CANCERS | BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2009-03-18 | — | — | EP | disclosed |
| US-20090004293-A1 | Phosphorous Containing Compounds Including Triphenylmethylphosphonate Esters for the Treatment of Melanoma and Other Cancers | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2009-01-01 | — | — | US | disclosed |
| WO-2007137200-A2 | PHOSPHOROUS CONTAINING COMPOUNDS INCLUDING TRIPHENYLMETHYLPHOSPHONATE ESTERS FOR THE TREATMENT OF MELANOMA AND OTHER CANCERS | BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2007-11-29 | — | — | WO | disclosed |