⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18952898 | 0.65 | — | — | |
| SCHEMBL352364 | 0.63 | PIK3CG (0.39) | — | |
| SCHEMBL16398092 | 0.63 | APOBEC3A (0.36) | — | |
| SCHEMBL17332613 | 0.63 | SMPD3 (0.40) | — | |
| SCHEMBL11115528 | 0.62 | — | — | |
| SCHEMBL1553537 | 0.58 | — | — | |
| SCHEMBL3264073 | 0.58 | — | — | |
| SCHEMBL845287 | 0.58 | — | — | |
| Hydrochloric Acid SCHEMBL29725195 | 0.56 | SMPD3 (0.38) | — | |
| SCHEMBL20564465 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10450320-B2 | Hexahydropyrazinotriazinone derivatives as kinase inhibitors | UCB BIOPHARMA SPRL (BE) | 2019-10-22 | — | — | US | claimed |
| US-20180362532-A1 | Hexahydropyrazinotriazinone Derivatives as Kinase Inhibitors | UCB BIOPHARMA SPRL (BE) | 2018-12-20 | — | — | US | claimed |
| EP-3386984-A1 | HEXAHYDROPYRAZINOTRIAZINONE DERIVATIVES AS KINASE INHIBITORS | UCB Biopharma SPRL (BE) | 2018-10-17 | — | — | EP | claimed |
| WO-2017097871-A1 | HEXAHYDROPYRAZINOTRIAZINONE DERIVATIVES AS KINASE INHIBITORS | UCB BIOPHARMA SPRL (BE) | 2017-06-15 | — | — | WO | claimed |
| US-7393873-B2 | Arylsulfonamide derivatives | MERCK & CO., INC. (US) | 2008-07-01 | — | — | US | claimed |
| US-20060142612-A1 | Arylsulfonamide derivatives | MERCK SHARP & DOHME CORP. | 2006-06-29 | — | — | US | claimed |
| EP-1643960-A2 | ARYLSULFONAMIDE DERIVATIVES | Merck & Co., Inc. (US) | 2006-04-12 | — | — | EP | claimed |
| WO-2005004810-A2 | ARYLSULFONAMIDE DERIVATIVES | MERCK & CO., INC. (US) | 2005-01-20 | — | — | WO | claimed |
| US-5322845-A | Controlling plant diseases | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1994-06-21 | — | — | US | claimed |
| US-5300497-A | Broad spectrum antibiotics and bactericides; stable to beta-lactamase; effective against antibiotic-resistant bacteria | TOYAMA CHEMICAL CO., LTD. (JP) | 1994-04-05 | — | — | US | claimed |
| US-5185330-A | Penicillins/ad/ | TOYAMA CHEMICAL CO., LTD. (JP) | 1993-02-09 | — | — | US | claimed |
| WO-2023222116-A1 | USE OF STEROID COMPOUND | 广州润尔眼科生物科技有限公司 | 2023-11-23 | — | — | WO | disclosed |
| US-20210070747-A1 | 2(1H)-QUINOLINONE DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2021-03-11 | — | — | US | disclosed |
| EP-3604281-A1 | 2(1H)-QUINOLINONE DERIVATIVE | Taisho Pharmaceutical Co., Ltd. (JP) | 2020-02-05 | — | — | EP | disclosed |
| US-10450320-B2 | Hexahydropyrazinotriazinone derivatives as kinase inhibitors | UCB BIOPHARMA SPRL (BE) | 2019-10-22 | — | — | US | disclosed |
| US-20030073733-A1 | Pharmaceutically active compounds and methods of use | KING PHARMACEUTICALS RESEARCH AND DEVELOPMENT, INC. | 2003-04-17 | — | — | US | disclosed |
| WO-2002083083-A2 | PHARMACEUTICALLY ACTIVE COMPOUNDS AND METHODS OF USE | KING PHARMACEUTICALS, INC. (US) | 2002-10-24 | — | — | WO | disclosed |
| US-5300497-A | Broad spectrum antibiotics and bactericides; stable to beta-lactamase; effective against antibiotic-resistant bacteria | TOYAMA CHEMICAL CO., LTD. (JP) | 1994-04-05 | — | — | US | disclosed |
| US-5185330-A | Penicillins/ad/ | TOYAMA CHEMICAL CO., LTD. (JP) | 1993-02-09 | — | — | US | disclosed |
| US-5026842-A | Reacting 7-aminocephalosporanic acid with a carboxylic acid in the presence of a dehydration condensation agent and acid | AJINOMOTO CO., INC. (JP) | 1991-06-25 | — | — | US | disclosed |