SCHEMBL845287

SCHEMBL845287

c1cnc2cnnn2c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL29725195 0.98 SMPD3 (0.38)
SCHEMBL19229514 0.73
SCHEMBL15830149 0.70
SCHEMBL19173 0.67
SCHEMBL31674379 0.65 PDE10A (0.45)
SCHEMBL31338725 0.65 PDE10A (0.45)
Hydrochloric Acid SCHEMBL6894527 0.65 PDE10A (0.45)
SCHEMBL64580 0.64
SCHEMBL30708692 0.64 APOBEC3A (0.61)
SCHEMBL334944 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 282 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4107159-A1 5-(3-(ETHYLSULFONYL)PYRIDIN-2-YL)-PYRAZOLO[1,5-A]PYRIMIDINE DERIVATIVES AND RELATED COMPOUNDS AS PESTICIDE AND INSECTICIDE AGENTS FOR CROP PROTECTION PI Industries Ltd. (IN) 2022-12-28 EP claimed
WO-2021113266-A1 TREATING COGNITIVE DISORDERS USING TRAPIDIL SINOPIA BIOSCIENCES, INC. (US) 2021-06-10 WO claimed
US-20160159808-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2016-06-09 US claimed
EP-3026051-A1 HETEROCYCLIC COMPOUND Takeda Pharmaceutical Company Limited (JP) 2016-06-01 EP claimed
EP-2318394-B1 NOVEL PHENYLIMIDAZOLE DERIVATIVES AS PDE10A ENZYME INHIBITORS LUNDBECK & CO AS H (DK) 2014-01-22 EP claimed
WO-2013148813-A1 TRIAZOLOTHIENOPYRIMIDINE COMPOUND INHIBITORS OF UREA TRANSPORTERS AND METHODS OF USING INHIBITORS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2013-10-03 WO claimed
US-8182718-B2 Ligand exchange thermochromic systems and high ε ligands for same PLEOTINT, L.L.C. (US) 2012-05-22 US claimed
EP-2082005-A1 LIGAND EXCHANGE THERMOCHROMIC, (LETC), SYSTEMS Pleotint, L.L.C. (US) 2009-07-29 EP claimed
JP-4295827-B2 2009-07-15 JP claimed
US-20080105851-A1 Exhibiting a reversible change in absorbance of electromagnetic radiation as the temperature of the system is reversibly changed; comprising a transition metal ion and a ligand PLEOTINT, LLC (US) 2008-05-08 US claimed
WO-1998035944-A1 AMIDES AS NPY5 RECEPTOR ANTAGONISTS BAYER CORPORATION (US) 1998-08-20 WO claimed
EP-0845026-A1 MULTICOMPONENT SYSTEM FOR USE WITH DETERGENT SUBSTANCES CALL, Hans-Peter Dr. (DE) 1998-06-03 EP claimed
WO-1998021178-A1 N-ARYLSULFILIMINE COMPOUNDS AND THEIR USE AS CATALYSTS IN THE PREPARATION OF N-ARYLARYLSULFONAMIDE COMPOUNDS DOW AGROSCIENCES LLC (US) 1998-05-22 WO claimed
WO-1997048786-A1 MULTICOMPONENT SYSTEM FOR USE WITH DETERGENT SUBSTANCES CALL HANS PETER (DE) 1997-12-24 WO claimed
EP-0723546-A1 1,2,4 - Triazolo (1,5-a) pyrimitives and their use for treatment of neurological disorders Knoll AG (DE) 1996-07-31 EP claimed
WO-1995010521-A1 THERAPEUTIC AGENTS KNOLL AG (DE) 1995-04-20 WO claimed
US-4871653-A DEVELOPING IN PRESENCE OF MERCAPTO POLYAZAINDENE PROMOTERS AND NUCLEATING QUATERNARY OR HYDRAZIDE-TYPE COMPOUNDS FUJI PHOTO FILM CO., LTD. (JP) 1989-10-03 US claimed
EP-0101517-B1 NOVEL S-TRIAZOLE(1,5-A)PYRIMIDINE DERIVATIVES MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 1986-10-29 EP claimed
EP-0178029-A2 Detergent compositions containing compatible organic emetic agent THE PROCTER & GAMBLE COMPANY (US) 1986-04-16 EP claimed
EP-0101517-A1 NOVEL s-TRIAZOLE(1,5-a)PYRIMIDINE DERIVATIVES MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 1984-02-29 EP claimed