Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Glycerin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.30 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycerin SCHEMBL27263776 | 0.94 | TP53 (0.58) | TP53LMNAALDH1A1THRBMEN1 | |
| Glycerin SCHEMBL28307053 | 0.94 | TP53 (0.58) | TP53LMNAALDH1A1THRBMEN1 | |
| Glycerin SCHEMBL11173648 | 0.94 | TP53 (0.58) | TP53LMNAALDH1A1THRBMEN1 | |
| Glycerin SCHEMBL1712541 | 0.94 | TP53 (0.58) | TP53LMNAALDH1A1THRBMEN1 | |
| Glycerin SCHEMBL29119754 | 0.94 | TP53 (0.58) | TP53LMNAALDH1A1THRBMEN1 | |
| Glycerin SCHEMBL1712543 | 0.94 | TP53 (0.58) | TP53LMNAALDH1A1THRBMEN1 | |
| Glycerin SCHEMBL2856963 | 0.94 | TP53 (0.58) | TP53LMNAALDH1A1THRBMEN1 | |
| Glycerin SCHEMBL29119760 | 0.94 | TP53 (0.58) | TP53LMNAALDH1A1THRBMEN1 | |
| Glycerin SCHEMBL27823536 | 0.91 | TP53 (0.55) | TP53LMNAALDH1A1THRBMEN1 | |
| Glycerin SCHEMBL28447412 | 0.88 | TP53 (0.52) | TP53LMNAALDH1A1THRBOR51E2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117535218-A | Chicken rhinitis genetically engineered escherichia coli high-density fermentation medium and fermentation process thereof | 山东滨州博莱威生物技术有限公司 | 2024-02-09 | — | — | CN | disclosed |
| US-20210254056-A1 | IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS | CAMP4 THERAPEUTICS CORPORATION | 2021-08-19 | — | — | US | disclosed |
| WO-2018204764-A1 | IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS | CAMP4 THERAPEUTICS CORPORATION (US) | 2018-11-08 | — | — | WO | disclosed |
| CN-107892634-A | The cotton dedicated liquid set meal fertilizer and preparation method and application process of a kind of improved soil | 新疆慧尔农业集团股份有限公司 | 2018-04-10 | — | — | CN | disclosed |
| CN-104891537-B | Comprehensive utilization method of silicate minerals | 南阳东方应用化工研究所 | 2017-05-17 | — | — | CN | disclosed |
| CN-104891537-A | Comprehensive utilization method of silicate minerals | NANYANG ORIENTAL APPLIC CHEMICAL RES INST | 2015-09-09 | — | — | CN | disclosed |
| WO-2010054482-A1 | IMMUNOGENIC HUMAN PAPILLOMAVIRUS COMPOSITIONS | NVENTA BIOPHARMACEUTICALS CORPORATION (US) | 2010-05-20 | — | — | WO | disclosed |
| CN-1272783-A | Dermatological compositions | BOOTS CO PLC (GB) | 2000-11-08 | — | — | CN | disclosed |