Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 10/20 | 0.46 |
| ▸ | CD63 | P08962 | 2/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.46 |
| ▸ | BRAF | P15056 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | CLK1 | P49759 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3360065 | 0.92 | PIK3CG (0.41) | SYKCD63PIK3CGBRAFPIK3CA | |
| SCHEMBL3360824 | 0.90 | BRAF (0.40) | SYKCD63PIK3CGBRAFEGFR | |
| SCHEMBL3359807 | 0.79 | FYN (0.41) | SYKCD63BRAFPIK3CAMAPT | |
| SCHEMBL3359890 | 0.78 | ABCG2 (0.36) | SYKCD63BRAFMAPK8MAPK9 | |
| SCHEMBL3362467 | 0.77 | ZAP70 (0.49) | PIK3CAZAP70 | |
| SCHEMBL3358704 | 0.76 | PIK3CA (0.44) | SYKCD63PIK3CGMAPK9PIK3CA | |
| SCHEMBL3358964 | 0.75 | ZAP70 (0.44) | SYKEGFRZAP70 | |
| SCHEMBL3362294 | 0.74 | BCHE (0.45) | SYKEGFR | |
| SCHEMBL3362714 | 0.73 | ABL1 (0.45) | SYKCD63PIK3CGPIK3CAMAPT | |
| SCHEMBL3362688 | 0.73 | SYK (0.32) | SYKPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2238137-A1 | COMPOUNDS AND COMPOSITIONS AS KINASE INHIBITORS | IRM LLC (BM) | 2010-10-13 | — | — | EP | disclosed |
| WO-2009097287-A1 | COMPOUNDS AND COMPOSITIONS AS KINASE INHIBITORS | IRM LLC (BM) | 2009-08-06 | — | — | WO | disclosed |