Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.47 |
| ▸ | RARB | P10826 | 2/20 | 0.42 |
| ▸ | RARA | P10276 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.39 |
| ▸ | NCF1 | P14598 | 3/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3358155 | 0.93 | APP (0.50) | APPRARBRARAALDH1A1MAPK1 | |
| SCHEMBL2799628 | 0.85 | APP (0.43) | APPRARBRARAKDM4EALDH1A1 | |
| SCHEMBL3354848 | 0.84 | BRAF (0.38) | APPRARBALDH1A1 | |
| SCHEMBL14836106 | 0.81 | APP (0.53) | APPALDH1A1MAPK1 | |
| SCHEMBL2798800 | 0.81 | APP (0.63) | APPRARBRARAKDM4EALDH1A1 | |
| SCHEMBL2799769 | 0.79 | APP (0.46) | APPRARBRARAALDH1A1MAPK1 | |
| SCHEMBL2802807 | 0.77 | APP (0.60) | APPKDM4ETDP1MAPK1ABL1 | |
| SCHEMBL2801603 | 0.76 | APP (0.63) | APPKDM4ETDP1MAPK1NCF1 | |
| SCHEMBL2799466 | 0.76 | APP (0.63) | APPKDM4EALDH1A1TDP1MAPK1 | |
| SCHEMBL2800869 | 0.76 | PAX8 (0.39) | RARBRARAKDM4EALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2144916-A1 | PHEN-NAPHTHALENE AND PHEN-QUINOLINE DERIVATIVES AND THEIR USE FOR BINDING AND IMAGING AMYLOID PLAQUES | The Trustees of the University of Pennsylvania (US) | 2010-01-20 | — | — | EP | disclosed |
| WO-2008124812-A1 | PHEN-NAPHTHALENE AND PHEN-QUINOLINE DERIVATIVES AND THEIR USE FOR BINDING AND IMAGING AMYLOID PLAQUES | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2008-10-16 | — | — | WO | disclosed |