Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | FABP6 | P51161 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CHEK2 | O96017 | 3/20 | 0.43 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NR2E3 | Q9Y5X4 | 2/20 | 0.42 |
| ▸ | ACP1 | P24666 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL335288 | 0.94 | MAPT (0.54) | ABL1FABP6MAPTPOLBLMNA | |
| SCHEMBL15282160 | 0.94 | ABL1 (0.42) | ABL1FABP6MAPTPOLBLMNA | |
| SCHEMBL336367 | 0.94 | MAPT (0.47) | ABL1FABP6MAPTPOLBLMNA | |
| SCHEMBL335878 | 0.91 | ABL1 (0.43) | ABL1FABP6MAPTPOLBLMNA | |
| SCHEMBL335576 | 0.90 | ABL1 (0.43) | ABL1FABP6MAPTPOLBLMNA | |
| SCHEMBL336586 | 0.90 | GRIN1 (0.44) | ABL1FABP6CHEK2ACP1F9 | |
| SCHEMBL8219489 | 0.90 | F9 (0.43) | ABL1FABP6MAPTDGAT1SMN1; SMN2 | |
| SCHEMBL335390 | 0.90 | ABL1 (0.44) | ABL1FABP6MAPTPOLBCHEK2 | |
| SCHEMBL336448 | 0.89 | TYMS (0.45) | ABL1FABP6MAPTACP1F9 | |
| SCHEMBL335501 | 0.89 | NPC1 (0.43) | ABL1FABP6MAPTCHEK2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8097758-B2 | Isoserine derivatives for use as coagulation factor IXa inhibitors | SANOFI-AVENTIS (FR) | 2012-01-17 | — | — | US | claimed |