Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | FABP6 | P51161 | 1/20 | 0.44 |
| ▸ | PIN1 | Q13526 | 4/20 | 0.44 |
| ▸ | ACP1 | P24666 | 1/20 | 0.41 |
| ▸ | F9 | P00740 | 2/20 | 0.41 |
| ▸ | F7 | P08709 | 2/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | F11 | P03951 | 1/20 | 0.38 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL335500 | 0.92 | F9 (0.44) | ABL1FABP6F9F7MEN1 | |
| SCHEMBL336367 | 0.91 | MAPT (0.47) | ABL1FABP6ACP1F9F7 | |
| SCHEMBL335878 | 0.90 | ABL1 (0.43) | ABL1FABP6ACP1F9F7 | |
| SCHEMBL335948 | 0.90 | ABL1 (0.45) | ABL1FABP6ACP1F9F7 | |
| SCHEMBL336586 | 0.89 | GRIN1 (0.44) | ABL1FABP6ACP1F9F7 | |
| SCHEMBL334843 | 0.89 | KDR (0.45) | ABL1FABP6F9F7MEN1 | |
| SCHEMBL8219489 | 0.88 | F9 (0.43) | ABL1FABP6ACP1F9F7 | |
| SCHEMBL335576 | 0.88 | ABL1 (0.43) | ABL1FABP6ACP1F9F7 | |
| SCHEMBL335205 | 0.87 | TYMS (0.42) | ABL1FABP6ACP1F9F7 | |
| SCHEMBL335420 | 0.87 | NPC1 (0.46) | ABL1FABP6F9F7MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8097758-B2 | Isoserine derivatives for use as coagulation factor IXa inhibitors | SANOFI-AVENTIS (FR) | 2012-01-17 | — | — | US | claimed |