Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 5/20 | 1.00 |
| ▸ | RAD52 | P43351 | 5/20 | 1.00 |
| ▸ | RAB9A | P51151 | 4/20 | 0.80 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.80 |
| ▸ | GAA | P10253 | 3/20 | 0.80 |
| ▸ | LMNA | P02545 | 3/20 | 0.80 |
| ▸ | GLA | P06280 | 2/20 | 0.80 |
| ▸ | MITF | O75030 | 2/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.80 |
| ▸ | TTR | P02766 | 1/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.69 |
| ▸ | SLC2A1 | P11166 | 4/20 | 0.69 |
| ▸ | NPC1 | O15118 | 2/20 | 0.69 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.69 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.69 |
| ▸ | TERT | O14746 | 1/20 | 0.63 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.59 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.57 |
| ▸ | TOP2A | P11388 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15867120 | 0.93 | POLB (0.87) | POLBRAD52RAB9AKDM4EGAA | |
| SCHEMBL15868024 | 0.90 | POLB (0.82) | POLBRAD52RAB9AKDM4EGAA | |
| SCHEMBL17154415 | 0.89 | POLB (1.00) | POLBRAD52RAB9AKDM4EGAA | |
| SCHEMBL7869214 | 0.89 | POLB (0.79) | POLBRAD52RAB9AKDM4EGAA | |
| SCHEMBL5578493 | 0.89 | POLB (0.79) | POLBRAD52RAB9AKDM4EGAA | |
| SCHEMBL13856923 | 0.87 | POLB (0.77) | POLBRAD52RAB9AKDM4EGAA | |
| SCHEMBL6033155 | 0.87 | POLB (0.77) | POLBRAD52RAB9AKDM4EGAA | |
| SCHEMBL7880366 | 0.85 | POLB (0.78) | POLBRAD52RAB9AKDM4EGAA | |
| Hydrochloric Acid SCHEMBL18334834 | 0.84 | POLB (0.72) | POLBRAD52RAB9AKDM4EGAA | |
| SCHEMBL14740626 | 0.83 | POLB (0.81) | POLBRAD52RAB9AKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160354533-A1 | ADSORBING PATHOGEN-INACTIVATING COMPOUNDS WITH POROUS PARTICLES IMMOBILIZED IN A MATRIX | CERUS CORPORATION (US) | 2016-12-08 | — | — | US | disclosed |
| US-9259525-B2 | Adsorbing pathogen-inactivating compounds with porous particles immobilized in a matrix | CERUS CORPORATION (US) | 2016-02-16 | — | — | US | disclosed |
| EP-1508345-B1 | System and method for the reduction of small organic compounds from blood products | CERUS CORP (US) | 2013-09-25 | — | — | EP | disclosed |
| US-20100133160-A1 | ADSORBING PATHOGEN-INACTIVATING COMPOUNDS WITH POROUS PARTICLES IMMOBILIZED IN A MATRIX | CERUS CORPORATION | 2010-06-03 | — | — | US | disclosed |
| US-7611831-B2 | Adsorbing pathogen-inactivating compounds with porous particles immobilized in a matrix | CERUS CORPORATION (US) | 2009-11-03 | — | — | US | disclosed |
| US-20060093999-A1 | For reducing the concentration of low molecular weight compounds in a biological composition containing cells while substantially maintaining a desired biological activity; comprises highly porous adsorbent particles | CERUS CORPORATION | 2006-05-04 | — | — | US | disclosed |
| US-7037642-B2 | Removing compounds from blood products with porous particles immobilized in a matrix | CERUS CORPORATION (US) | 2006-05-02 | — | — | US | disclosed |
| US-20050142542-A1 | ABSORBING PATHOGEN-INACTIVATING COMPOUNDS WITH POROUS PARTICLES IMMOBILIZED IN A MATRIX | CERUS CORPORATION | 2005-06-30 | — | — | US | disclosed |
| EP-1508345-A1 | Absorbents and devices for the reduction of small organic compounds from blood products | Cerus Corporation (US) | 2005-02-23 | — | — | EP | disclosed |
| EP-0954374-B1 | ADSORBENS AND DEVICES FOR THE REDUCTION OF SMALL ORGANIC COMPOUNDS FROM BLOOD PRODUCTS | CERUS CORP (US) | 2004-11-24 | — | — | EP | disclosed |
| US-20020094568-A1 | Batch devices for the reduction of compounds from biological compositions containing cells and methods of use | HEI DEREK J (US) | 2002-07-18 | — | — | US | disclosed |
| US-20020045228-A1 | Batch devices for the reduction of compounds from biological compositions containing cells and methods of use | CERUS CORPORATION | 2002-04-18 | — | — | US | disclosed |
| US-20010018179-A1 | BATCH DEVICES FOR THE REDUCTION OF COMPOUNDS FROM BIOLOGICAL COMPOSITIONS CONTAINING CELLS AND METHODS OF USE | CERUS CORPORATION | 2001-08-30 | — | — | US | disclosed |
| US-20010009756-A1 | FLOW DEVICES FOR THE REDUCTION OF COMPOUNDS FROM BIOLOGICAL COMPOSITIONS AND METHODS OF USE | CERUS CORPORATION | 2001-07-26 | — | — | US | disclosed |
| EP-1051249-A1 | FLOW DEVICES FOR THE REDUCTION OF COMPOUNDS FROM BIOLOGICAL COMPOSITIONS AND METHODS OF USE | Cerus Corporation (US) | 2000-11-15 | — | — | EP | disclosed |
| EP-1044066-A1 | BATCH DEVICES FOR THE REDUCTION OF COMPOUNDS FROM BIOLOGICAL COMPOSITIONS CONTAINING CELLS AND METHODS OF USE | Cerus Corporation (US) | 2000-10-18 | — | — | EP | disclosed |
| EP-0954374-A1 | METHODS AND DEVICES FOR THE REDUCTION OF SMALL ORGANIC COMPOUNDS FROM BLOOD PRODUCTS | Cerus Corporation (US) | 1999-11-10 | — | — | EP | disclosed |
| WO-1999034914-A1 | BATCH DEVICES FOR THE REDUCTION OF COMPOUNDS FROM BIOLOGICAL COMPOSITIONS CONTAINING CELLS AND METHODS OF USE | CERUS CORPORATION (US) | 1999-07-15 | — | — | WO | disclosed |
| WO-1999034915-A1 | FLOW DEVICES FOR THE REDUCTION OF COMPOUNDS FROM BIOLOGICAL COMPOSITIONS AND METHODS OF USE | CERUS CORPORATION (US) | 1999-07-15 | — | — | WO | disclosed |
| WO-1998030327-A1 | METHODS AND DEVICES FOR THE REDUCTION OF SMALL ORGANIC COMPOUNDS FROM BLOOD PRODUCTS | CERUS CORPORATION (US) | 1998-07-16 | — | — | WO | disclosed |