Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.77 |
| ▸ | RAD52 | P43351 | 4/20 | 0.77 |
| ▸ | RAB9A | P51151 | 2/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.70 |
| ▸ | MITF | O75030 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | TTR | P02766 | 1/20 | 0.70 |
| ▸ | GLA | P06280 | 1/20 | 0.70 |
| ▸ | GAA | P10253 | 1/20 | 0.70 |
| ▸ | SLC2A1 | P11166 | 3/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | NPC1 | O15118 | 1/20 | 0.70 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.70 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.70 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.69 |
| ▸ | BCHE | P06276 | 9/20 | 0.62 |
| ▸ | ACHE | P22303 | 8/20 | 0.62 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.62 |
| ▸ | GABRP | O00591 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13856923 | 1.00 | POLB (0.77) | POLBRAD52RAB9AKDM4EMITF | |
| SCHEMBL5578493 | 0.98 | POLB (0.79) | POLBRAD52RAB9AKDM4EMITF | |
| Hydrochloric Acid SCHEMBL18334834 | 0.96 | POLB (0.72) | POLBRAD52RAB9AKDM4EMITF | |
| SCHEMBL7869214 | 0.94 | POLB (0.79) | POLBRAD52RAB9AKDM4EMITF | |
| SCHEMBL9415866 | 0.91 | SLC2A1 (0.75) | POLBRAD52RAB9AKDM4EMITF | |
| SCHEMBL15867120 | 0.91 | POLB (0.87) | POLBRAD52RAB9AKDM4EMITF | |
| SCHEMBL11934972 | 0.91 | ACHE (0.67) | POLBRAD52RAB9AKDM4EMITF | |
| SCHEMBL8213149 | 0.91 | POLB (0.70) | POLBRAD52RAB9AKDM4EMITF | |
| Hydrochloric Acid SCHEMBL8651166 | 0.90 | SLC2A1 (0.78) | POLBRAD52RAB9AKDM4EMITF | |
| Hydrochloric Acid SCHEMBL8065778 | 0.90 | ACHE (0.65) | POLBRAD52RAB9AKDM4EMITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024189607-A1 | METHODS AND BIOAVAILABLE HIGHLY PERMEABLE COMPOUNDS FOR DISEASES TREATMENT | DIDENKO KIRILL (MX) | 2024-09-19 | — | — | WO | disclosed |
| US-7144738-B2 | Materials for enhancing staining of biopolymers in matrices | WHITNEY SCOTT | 2006-12-05 | — | — | US | disclosed |
| US-20050170517-A1 | Materials for enhancing staining of biopolymers in matrices | INVITROGEN CORPORATION (US) | 2005-08-04 | — | — | US | disclosed |
| US-6878551-B2 | For proteins/polypeptides within polyacrylamide matrix; mass spectrometry | INVITROGEN CORPORATION (US) | 2005-04-12 | — | — | US | disclosed |
| US-20040038418-A1 | Materials for enhancing staining of biopolymers in matrices | INVITROGEN CORPORATION | 2004-02-26 | — | — | US | disclosed |
| US-6635489-B2 | Sensitizing the matrix with heteroaromatic compounds, contacting with reduceable metal salts to stain and detecting | INVITROGEN CORPORATION | 2003-10-21 | — | — | US | disclosed |
| US-20020137222-A1 | Materials for enhancing staining of biopolymers in matrices | INVITROGEN CORPORATION | 2002-09-26 | — | — | US | disclosed |
| US-4812449-A | SYNTHESIS AT TARGET SITES, MICROENVIRONMENT | SCRIPPS CLINIC AND RESEARCH FOUNDATION (US) | 1989-03-14 | — | — | US | disclosed |
| EP-0175371-A2 | Method for silver staining proteins and nucleic acids | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-03-26 | — | — | EP | disclosed |
| US-4575452-A | Kit for silver staining proteins and nucleic acids | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-03-11 | — | — | US | disclosed |