Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPA5 | P11021 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.34 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.33 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL275967 | 0.91 | SMN1; SMN2 (0.49) | HSPA5SMN1; SMN2CYP2C9CYP2C19HIF1A | |
| SCHEMBL475645 | 0.87 | HSPA5 (0.63) | HSPA5SMN1; SMN2CYP2C9CYP2C19HIF1A | |
| SCHEMBL4413753 | 0.87 | HSPA5 (0.63) | HSPA5SMN1; SMN2CYP2C9CYP2C19HIF1A | |
| SCHEMBL7189547 | 0.80 | HSPA5 (0.50) | HSPA5SMN1; SMN2CYP2C9CYP2C19HIF1A | |
| SCHEMBL9114680 | 0.78 | HSPA5 (0.66) | HSPA5SMN1; SMN2CYP2C9CYP2C19HIF1A | |
| SCHEMBL19732823 | 0.77 | HSPA5 (0.49) | HSPA5SMN1; SMN2CYP2C9CYP2C19HIF1A | |
| SCHEMBL28981884 | 0.77 | HSPA5 (0.71) | HSPA5SMN1; SMN2CYP2C9CYP2C19HIF1A | |
| SCHEMBL3359612 | 0.76 | HSPA5 (0.55) | HSPA5SMN1; SMN2CYP2C9CYP2C19HIF1A | |
| SCHEMBL2698991 | 0.76 | CYP2C9 (0.61) | HSPA5SMN1; SMN2CYP2C9CYP2C19HIF1A | |
| SCHEMBL10381211 | 0.76 | HSPA5 (0.53) | HSPA5SMN1; SMN2CYP2C9CYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100255317-A1 | POLYURETHANE COMPOSITION | KURARAY CO., LTD. (JP) | 2010-10-07 | — | — | US | disclosed |
| EP-2208760-A1 | POLYURETHANE COMPOSITION | Kuraray Co., Ltd. (JP) | 2010-07-21 | — | — | EP | disclosed |