Sugi Predict

Sugi Predict / Compounds / SCHEMBL4413753

SCHEMBL4413753

SCHEMBL4413753

Cc1cc(Cc2cc(C)cc(C(C)(C)C)c2/C=C/C(=O)O)c(O)c(C(C)(C)C)c1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HSPA5 P11021 2/20 0.63
▸ HIF1A Q16665 4/20 0.61
▸ SMN1; SMN2 Q16637 4/20 0.61
▸ CYP2C9 P11712 3/20 0.61
▸ CYP2C19 P33261 3/20 0.61
▸ CYP2D6 P10635 2/20 0.56
▸ HSD17B10 Q99714 1/20 0.56
▸ ALDH1A1 P00352 3/20 0.44
▸ CA2 P00918 1/20 0.44
▸ POLB P06746 1/20 0.44
▸ TYR P14679 1/20 0.44
▸ GABBR2 O75899 2/20 0.40
▸ GABBR1 Q9UBS5 2/20 0.40
▸ TNFRSF1A P19438 1/20 0.36
▸ GLRA3 O75311 1/20 0.36
▸ GLRB P48167 1/20 0.36
▸ TP53 P04637 1/20 0.35
▸ PTGS1 P23219 1/20 0.35
▸ PTGS2 P35354 1/20 0.35
▸ AKR1B10 O60218 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL475645 1.00 HSPA5 (0.63) HSPA5HIF1ASMN1; SMN2CYP2C9CYP2C19
SCHEMBL7189547 0.93 HSPA5 (0.50) HSPA5HIF1ASMN1; SMN2CYP2C9CYP2C19
SCHEMBL19732823 0.89 HSPA5 (0.49) HSPA5HIF1ASMN1; SMN2CYP2C9CYP2C19
SCHEMBL3359609 0.87 HSPA5 (0.53) HSPA5HIF1ASMN1; SMN2CYP2C9CYP2C19
SCHEMBL275967 0.87 SMN1; SMN2 (0.49) HSPA5HIF1ASMN1; SMN2CYP2C9CYP2C19
SCHEMBL3353518 0.87 HSPA5 (0.44) HSPA5HIF1ASMN1; SMN2CYP2C9CYP2C19
SCHEMBL4220907 0.83 SMN1; SMN2 (0.49) HSPA5HIF1ASMN1; SMN2CYP2C9CYP2C19
SCHEMBL15464152 0.83 HSPA5 (0.55) HSPA5HIF1ASMN1; SMN2CYP2C9CYP2C19
SCHEMBL2698991 0.83 CYP2C9 (0.61) HSPA5HIF1ASMN1; SMN2CYP2C9CYP2C19
Acrylic Acid SCHEMBL9820642 0.82 HSPA5 (0.73) HSPA5HIF1ASMN1; SMN2CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230190655-A1 METHODS FOR CONSOLIDATING ANTIBIOTIC-ELUTING POLYMERIC MATERIALS THE GENERAL HOSPITAL CORPORATION 2023-06-22 — — US disclosed
US-20230190655-A1 METHODS FOR CONSOLIDATING ANTIBIOTIC-ELUTING POLYMERIC MATERIALS THE GENERAL HOSPITAL CORPORATION 2023-06-22 — — US disclosed
US-20220002452-A1 SURFACE GRADIENT CROSS-LINKING METHOD OF ULTRA-HIGH MOLECULAR WEIGHT POLYETHYLENE AND THE APPLICATION THEREOF b-ONE Medical (Suzhou) Co., Ltd. (CN) 2022-01-06 — — US disclosed
US-10981302-B2 Peroxide cross-linking and high temperature melting THE GENERAL HOSPITAL CORPORATION (US) 2021-04-20 — — US disclosed
US-10953136-B2 Systems and methods of radioprotection of allografts THE GENERAL HOSPITAL CORPORATION (US) 2021-03-23 — — US disclosed
US-20190255744-A1 PEROXIDE CROSS-LINKING AND HIGH TEMPERATURE MELTING THE GENERAL HOSPITAL CORPORATION (US) 2019-08-22 — — US disclosed
US-20190167852-A1 SYSTEMS AND METHODS OF RADIOPROTECTION OF ALLOGRAFTS THE GENERAL HOSPITAL CORPORATION (US) 2019-06-06 — — US disclosed
US-10220547-B2 Peroxide cross-linking and high temperature melting THE GENERAL HOSPITAL CORPORATION (US) 2019-03-05 — — US disclosed
US-10000305-B2 Antioxidant-stabilized joint implants THE GENERAL HOSPITAL CORPORATION (US) 2018-06-19 — — US disclosed
US-10000305-B2 Antioxidant-stabilized joint implants THE GENERAL HOSPITAL CORPORATION (US) 2018-06-19 — — US disclosed
US-20160250779-A1 PEROXIDE CROSS-LINKING AND HIGH TEMPERATURE MELTING THE GENERAL HOSPITAL CORPORATION 2016-09-01 — — US disclosed
US-20160250779-A1 PEROXIDE CROSS-LINKING AND HIGH TEMPERATURE MELTING THE GENERAL HOSPITAL CORPORATION 2016-09-01 — — US disclosed
US-20160215117-A1 PEROXIDE CROSS-LINKING OF POLYMERIC MATERIALS IN THE PRESENCE OF ANTIOXIDANTS THE GENERAL HOSPITAL CORPORATION 2016-07-28 — — US disclosed
US-20160215117-A1 PEROXIDE CROSS-LINKING OF POLYMERIC MATERIALS IN THE PRESENCE OF ANTIOXIDANTS THE GENERAL HOSPITAL CORPORATION 2016-07-28 — — US disclosed
US-20150368375-A1 Methods For Making Crosslinked Ultra High Molecular Weight Polyethylene BIOMET MANUFACTURING, LLC 2015-12-24 — — US disclosed
US-20150368375-A1 Methods For Making Crosslinked Ultra High Molecular Weight Polyethylene BIOMET MANUFACTURING, LLC 2015-12-24 — — US disclosed
US-20150151866-A1 ANTIOXIDANT-STABILIZED JOINT IMPLANTS THE GENERAL HOSPITAL CORPORATION 2015-06-04 — — US disclosed
US-20150151866-A1 ANTIOXIDANT-STABILIZED JOINT IMPLANTS THE GENERAL HOSPITAL CORPORATION 2015-06-04 — — US disclosed
US-7638565-B2 Polyacetal resin composition POLYPLASTICS CO., LTD. (JP) 2009-12-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10953136-B2 Systems and methods of radioprotection of allografts ERCC1, MGMT, XPA HSPA5 1173/4885HIF1A 1178/4885SMN1; SMN2 2950/4885
US-20190167852-A1 SYSTEMS AND METHODS OF RADIOPROTECTION OF ALLOGRAFTS ERCC1, MGMT, XPA HSPA5 1173/4885HIF1A 1178/4885SMN1; SMN2 2950/4885
US-20220002452-A1 SURFACE GRADIENT CROSS-LINKING METHOD OF ULTRA-HIGH MOLECULAR WEIGHT POLYETHYLENE AND THE APPLICATION THEREOF RPL7, PLAUR, CUTA HSPA5 418/4885HIF1A 1128/4885SMN1; SMN2 4690/4885
US-20230190655-A1 METHODS FOR CONSOLIDATING ANTIBIOTIC-ELUTING POLYMERIC MATERIALS PUF60, ALG1, PCBP1 HSPA5 949/4885HIF1A 2870/4885SMN1; SMN2 3031/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.