Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 3/20 | 0.64 |
| ▸ | LCK | P06239 | 1/20 | 0.64 |
| ▸ | FYN | P06241 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | THPO | P40225 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL15285365 | 1.00 | FFAR3 (0.64) | FFAR3LCKFYNALDH1A1TSHR | |
| Acetic Acid SCHEMBL15689783 | 1.00 | FFAR3 (0.64) | FFAR3LCKFYNALDH1A1TSHR | |
| Acetic Acid SCHEMBL17373805 | 1.00 | FFAR3 (0.64) | FFAR3LCKFYNALDH1A1TSHR | |
| Acetic Acid SCHEMBL3295221 | 1.00 | FFAR3 (0.64) | FFAR3LCKFYNALDH1A1TSHR | |
| Acetic Acid SCHEMBL15090782 | 1.00 | FFAR3 (0.64) | FFAR3LCKFYNALDH1A1TSHR | |
| Acetic Acid SCHEMBL15689725 | 1.00 | FFAR3 (0.64) | FFAR3LCKFYNALDH1A1TSHR | |
| Acetic Acid SCHEMBL36929 | 1.00 | — | — | |
| Acetic Acid SCHEMBL15391985 | 0.96 | — | — | |
| Acetic Acid SCHEMBL8854356 | 0.96 | FFAR3 (0.58) | FFAR3LCKFYNALDH1A1TSHR | |
| Acetic Acid SCHEMBL21489111 | 0.96 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119208685-A | Preparation method of GDC barrier layer, electrolyte and solid oxide cell | 上海交通大学 | 2024-12-27 | — | — | CN | claimed |
| CN-119208685-A | Preparation method of GDC barrier layer, electrolyte and solid oxide cell | 上海交通大学 | 2024-12-27 | — | — | CN | disclosed |
| CN-116470089-A | Electrical contact layer for use in solid oxide fuel cell, method of making the same, and solid oxide fuel cell comprising the same | 上海交通大学 | 2023-07-21 | — | — | CN | disclosed |
| CN-115052873-A | Heteroaromatic carboxamide derivatives as plasma kallikrein inhibitors | 勃林格殷格翰国际有限公司 | 2022-09-13 | — | — | CN | disclosed |
| EP-2217696-A2 | NOVEL BACTERIA AND METHODS OF USE THEREOF | Lanzatech New Zealand Limited (NZ) | 2010-08-18 | — | — | EP | disclosed |
| WO-2009064200-A2 | NOVEL BACTERIA AND METHODS OF USE THEREOF | LANZATECH NEW ZEALAND LIMITED (NZ) | 2009-05-22 | — | — | WO | disclosed |
| US-6080281-A | PASSING CONTAMINATED AIR INTO CONTACT ZONE IN WHICH IS DISPOSED ADSORBENT WHICH CONSISTS OF AEROGEL MATERIAL CAPABLE OF SELECTIVELY ADSORBING SAID POLLUTANT FROM AIR AND THEREIN CONTACTING CONTAMINATED AIR WITH AEROGEL, WITHDRAWING AIR | ATTIA YOSRY A (US) | 2000-06-27 | — | — | US | disclosed |