⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL93879 | 0.82 | — | — | |
| SCHEMBL6789438 | 0.69 | — | — | |
| SCHEMBL16496844 | 0.67 | — | — | |
| SCHEMBL7002573 | 0.65 | — | — | |
| SCHEMBL16588569 | 0.65 | — | — | |
| SCHEMBL727141 | 0.65 | — | — | |
| SCHEMBL13532427 | 0.65 | — | — | |
| SCHEMBL6617087 | 0.64 | — | — | |
| SCHEMBL9158543 | 0.63 | — | — | |
| SCHEMBL2400696 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12534435-B2 | Lipids and nanoparticle compositions thereof | GENERATION BIO CO. (US) | 2026-01-27 | — | — | US | disclosed |
| US-20250361208-A1 | LIPIDS AND NANOPARTICLE COMPOSITIONS THEREOF | GENERATION BIO CO (US) | 2025-11-27 | — | — | US | disclosed |
| US-12252470-B2 | Lipids and nanoparticle compositions thereof | GENERATION BIO CO. (US) | 2025-03-18 | — | — | US | disclosed |
| US-20240294474-A1 | NOVEL LIPIDS AND NANOPARTICLE COMPOSITIONS THEREOF | GENERATION BIO CO. | 2024-09-05 | — | — | US | disclosed |
| US-20230320993-A1 | METHODS FOR ENCAPSULATING POLYNUCLEOTIDES INTO REDUCED SIZES OF LIPID NANOPARTICLES AND NOVEL FORMULATION THEREOF | GENERATION BIO CO. | 2023-10-12 | — | — | US | disclosed |
| CN-116437964-A | Methods for encapsulating polynucleotides into reduced size lipid nanoparticles and novel formulations thereof | 世代生物公司 | 2023-07-14 | — | — | CN | disclosed |
| US-20230159459-A1 | NOVEL LIPIDS AND NANOPARTICLE COMPOSITIONS THEREOF | GENERATION BIO CO. | 2023-05-25 | — | — | US | disclosed |
| US-11649250-B2 | Pyrrolobenzodiazepine conjugates | MEDIMMUNE LIMITED (GB) | 2023-05-16 | — | — | US | disclosed |
| CN-115916163-A | Novel lipids and nanoparticle compositions thereof | 世代生物公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-114901690-A | Treatment of cancer with Antibody Drug Conjugates (ADCs) that bind 191P4D12 protein | 艾更斯司股份有限公司 | 2022-08-12 | — | — | CN | disclosed |
| EP-0918757-A1 | 8-HYDROCARBYL SUBSTITUTED BENZODIZOCINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS PROTEIN KINASE C (=PKC) MODULATORS | GEORGETOWN UNIVERSITY (US) | 1999-06-02 | — | — | EP | disclosed |
| WO-1997043268-A1 | 8-HYDROCARBYL SUBSTITUTED BENZODIZOCINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS PROTEIN KINASE C (=PKC) MODULATORS | GEORGETOWN UNIVERSITY (US) | 1997-11-20 | — | — | WO | disclosed |
| US-5446158-A | Process for synthesis of FK-506 and tricarbonyl intermediates | MERCK & CO., INC. (US) | 1995-08-29 | — | — | US | disclosed |
| EP-0378318-A1 | Process for synthesis of FK-506 and tricarbonyl intermediates | MERCK & CO. INC. (US) | 1990-07-18 | — | — | EP | disclosed |
| EP-0054795-B1 | NOVEL HALOGENATED PROSTACYCLINS, PROCESS FOR THE PRODUCTION THEREOF, AND PHARMACEUTICAL USE THEREOF | TEIJIN LIMITED (JP) | 1987-07-15 | — | — | EP | disclosed |
| EP-0077209-B1 | NITROGEN-CONTAINING PROSTACYCLIN ANALOGUES AND COMPOSITIONS CONTAINING THEM | THE UPJOHN COMPANY (US) | 1987-01-07 | — | — | EP | disclosed |
| US-4496742-A | Analogs of 5,6-dihydro PGI2 | THE UPJOHN COMPANY (US) | 1985-01-29 | — | — | US | disclosed |
| US-4472428-A | CARDIOVASCULAR DISORDERS, ORGAN TRANSPLANTS | TEIJIN LIMITED (JP) | 1984-09-18 | — | — | US | disclosed |
| EP-0077209-A1 | Nitrogen-containing prostacyclin analogues and compositions containing them | THE UPJOHN COMPANY (US) | 1983-04-20 | — | — | EP | disclosed |
| EP-0054795-A2 | Novel halogenated prostacyclins, process for the production thereof, and pharmaceutical use thereof | TEIJIN LIMITED (JP) | 1982-06-30 | — | — | EP | disclosed |