Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.42 |
| ▸ | KDR | P35968 | 4/20 | 0.42 |
| ▸ | FLT1 | P17948 | 2/20 | 0.42 |
| ▸ | FLT4 | P35916 | 2/20 | 0.42 |
| ▸ | PLK4 | O00444 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | INSR | P06213 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13270937 | 0.79 | MAPT (0.36) | ALDH1A1HPGDKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL5990519 | 0.74 | MAPKAPK2 (0.64) | ALDH1A1KDM4EMAPTMAPKAPK2SMN1; SMN2 | |
| SCHEMBL3359285 | 0.72 | MAPKAPK2 (0.46) | ALDH1A1HPGDKDM4EMAPTMAPKAPK2 | |
| SCHEMBL5990507 | 0.71 | CLK1 (0.51) | MAPKAPK2KDRFLT1FLT4PLK4 | |
| SCHEMBL1645118 | 0.70 | CHRNA7 (0.55) | ALDH1A1HPGDKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL12410466 | 0.70 | MAPKAPK2 (0.55) | ALDH1A1HPGDKDM4EMAPTMAPKAPK2 | |
| SCHEMBL5646211 | 0.69 | MAPKAPK2 (0.51) | MAPKAPK2SMN1; SMN2KDRFLT1FLT4 | |
| SCHEMBL12989203 | 0.68 | MAPKAPK2 (0.54) | ALDH1A1HPGDKDM4EMAPTMAPKAPK2 | |
| SCHEMBL182164 | 0.68 | MAPKAPK2 (0.79) | ALDH1A1KDM4EMAPTMAPKAPK2SMN1; SMN2 | |
| SCHEMBL13763422 | 0.67 | GAA (0.47) | MAPKAPK2KDRFLT1FLT4PLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2210887-A1 | Bis resorcinyl triazine derivatives as protecting agents against UV radiation | ISDIN, S.A. (ES) | 2010-07-28 | — | — | EP | disclosed |
| WO-2010081835-A2 | BIS-RESORCINYL-TRIAZINE DERIVATIVES AS PROTECTING AGENTS AGAINST UV RADIATION | ISDIN, S. A. (ES) | 2010-07-22 | — | — | WO | disclosed |